Effects of Time-Restricted Feeding and Ramadan Fasting on Body Weight, Body Composition, Glucose Responses, and Insulin Resistance: A Systematic Review of Randomized Controlled Trials
Tsitsou S, Zacharodimos N, Poulia KA, Karatzi K, Dimitriadis G, Papakonstantinou E
Nutrients · 43 citations
How it was studied
- Design
- Systematic review (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
Based on full-text disclosure statement.
Publication
- Published
- 2022-11-11 · Nutrients · vol. 14 · issue 22 · p. 4778
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 57 citations · more than 89% of similar papers · 2.0× the field average
- References
- 107 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Dietary Effects on Health · Circadian rhythm and melatonin · Diet and metabolism studies
- Keywords
- Overweight, Weight loss, Medicine, Glycemic, Obesity, Insulin resistance, Internal medicine, Endocrinology, Insulin, Intermittent fasting, Randomized controlled trial
- MeSH
- humans, insulin resistance, obesity, body weight, weight loss, glucose, blood glucose, fasting, body composition, overweight, randomized controlled trials as topic
6 authors
From GR
- Sofia TsitsouAgricultural University of Athens
- Nikolaos ZacharodimosAgricultural University of Athens
- Kalliopi‐Anna PouliaAgricultural University of Athens
- Kalliopi KaratziAgricultural University of Athens
- George DimitriadisNational and Kapodistrian University of Athens
- Emilia Papakonstantinou · correspondingAgricultural University of Athens
Abstract
Time-restricted feeding (TRF) and Ramadan fasting (RF) have been recently associated with several health outcomes. However, it is not yet clear if they are superior to existing treatments in terms of glucose metabolism, insulin action, and weight loss. This review aims to summarize the current data on the effects of these regimes on body weight, body composition, and glycemia. An electronic search was conducted in PUBMED and SCOPUS databases up to August 2022. Twenty-four records met the inclusion criteria and underwent a risk-of-bias assessment. The main outcomes were: (a) TRF may result in moderate weight loss in individuals with overweight/obesity; when TRF is combined with caloric restriction, weight loss is >5% of the initial body weight, (b) 14 h of fasting may be as effective as 16 h in terms of weight loss, and (c) TRF may lead to improved insulin sensitivity and glycemic responses/variability throughout the day in individuals with overweight/obesity. Concerning RF, only two studies were available and thus, conclusions were not drawn. TRF may be an effective nutritional approach for weight loss, and the amelioration of glycemic control and insulin sensitivity in individuals with overweight/obesity. However, more long-term, well-designed studies are needed.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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