Red, white, and processed meat consumption related to inflammatory and metabolic biomarkers among overweight and obese women
Shiraseb F, Hosseininasab D, Mirzababaei A, Bagheri R, Wong A, Suzuki K, Mirzaei K
Frontiers in nutrition · 31 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Cross-sectional study (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Food frequency questionnaire
Who paid for it
- Funding
- Independent funding
- University or hospital
- Tehran University of Medical Sciences and Health Services
- Grants
- Tehran University of Medical Sciences and Health Services (33142); Tehran University of Medical Sciences and Health Services (34479); Tehran University of Medical Sciences and Health Services (96-01-161-34479); Tehran University of Medical Sciences and Health Services (95-03-161-33142)
Based on 1 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2022-11-10 · Front Nutr · vol. 9 · p. 1015566
- Publisher
- Frontiers Media
- Cited
- 40 citations · more than 97% of similar papers · 6.4× the field average
- Impact
- Top 10% most cited in its field
- References
- 78 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Nutritional Studies and Diet · Dietary Effects on Health · Adipokines, Inflammation, and Metabolic Diseases
- Keywords
- Overweight, Consumption (sociology), Obesity, Medicine, White meat, Environmental health, White (mutation), Red meat, Food science, Internal medicine, Biology, Gene, Pathology, Biochemistry
7 authors
From IR, US, JP
- Farideh ShirasebTehran University of Medical Sciences
- Dorsa HosseininasabIslamic Azad University, Science and Research Branch
- Atieh MirzababaeiTehran University of Medical Sciences
- Reza BagheriUniversity of Isfahan
- Alexei WongMarymount University
- Katsuhiko SuzukiWaseda University
Abstract
Background
Considering that a high meat intake is directly associated with obesity, it is critical to address the relationship between consuming different types of meat with inflammation and metabolism in overweight and obese cohorts. Thus, we evaluated the association between red, white, and processed meat consumption with inflammatory and metabolic biomarkers in overweight and obese women.
Methods
The current cross-sectional study was conducted on 391 overweight and obese Iranian women. Dietary intake was obtained from a food frequency questionnaire (FFQ) with 147 items. The anthropometric measurements, serum lipid profile, and inflammatory markers were measured by standard protocols. All associations were assessed utilizing one-way analysis of variance (ANOVA), analysis of covariance (ANCOVA), and linear regression models.
Results
In the adjusted model, it was established that higher intake of processed meat had a significant positive association with leptin levels (β: 0.900, 95% CI: 0.031;1.233, p = 0.015). Moreover, after considering the confounders, a significant positive association between processed meat and macrophage inflammatory protein (MCP-1) levels was observed (β: 0.304, 95% CI:0.100;1.596, p = 0.025). Positive significant associations between high-sensitivity C-reactive protein (hs-CRP) (β:0.020, 95% CI:0.000;0.050, P = 0.014) and plasminogen activator inhibitor 1 (PAI-1) (β:0.263, 95% CI:0.112;0.345, p = 0.053) and MCP-1 (β:0.490, 95% CI: 0.175;1.464, p = 0.071) levels with red meat were also shown; while there was a significant negative association between red meat and the homeostasis model assessment of insulin resistance (HOMA-IR) (β: -0.016, 95% CI: -0.022, -0.001, p = 0.033). Furthermore, a significant negative association were established following confounding adjustment between Galectin-3 (Gal-3) (β: -0.110, 95% CI: -0.271;0.000, p = 0.044), MCP-1 (β: -1.933, 95% CI: -3.721;0.192, p = 0.022) and Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) (β: -0.011, 95% CI: -0.020,0.000, p = 0.070) levels with high adherence of white meat intake. In contrast, a significant marginally positive association between PAI-1 levels and high adherence to white meat intake (β: -0.340, 95% CI: -0.751;0.050, p = 0.070) has been shown.
Conclusions
Higher red and processed meat consumption were positively associated with inflammatory and metabolic markers in overweight and obese women. In contrast, negative relationships between high adherence to white meat and various inflammatory and metabolic parameters were established. Further studies are needed to confirm the causality of these associations and potential mediating pathways.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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