Transcranial photobiomodulation enhances visual working memory capacity in humans
Zhao C, Li D, Kong Y, Liu H, Hu Y, Niu H, Jensen O, Li X, Liu H, Song Y
Science advances · 66 citations
How it was studied
- Design
- Randomized controlled trial (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
- Nonprofit
- Wellcome Trust
- Government
- National Natural Science Foundation of China
- Government
- Ministry of Science and Technology of the People's Republic of China
- Government
- National Defense Basic Scientific Research Program of China
- Grants
- Wellcome Trust (207550/Z/17/Z); National Natural Science Foundation of China (31871099); Ministry of Science and Technology of the People's Republic of China (2021ZD0204300); National Natural Science Foundation of China (61761166003); National Natural Science Foundation of China (-2021ZD0204300); National Natural Science Foundation of China (2022ZD0211300); National Defense Basic Scientific Research Program of China (2018110B011)
Based on 4 listed funder(s).
Publication
- Published
- 2022-12-02 · Sci Adv · vol. 8 · issue 48 · p. eabq3211
- Publisher
- American Association for the Advancement of Science
- Cited
- 92 citations · more than 99% of similar papers · 9.9× the field average
- Impact
- Top 10% most cited in its field
- References
- 60 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Laser Applications in Dentistry and Medicine · Migraine and Headache Studies · Optical Imaging and Spectroscopy Techniques
- Keywords
- Working memory, Prefrontal cortex, Neuroscience, Transcranial direct-current stimulation, Set (abstract data type), Cognition, Psychology, Medicine, Stimulation, Cognitive psychology, Audiology, Computer science
10 authors
From CN, GB, US
- Chenguang Zhao · correspondingBeijing Normal University; Chinese Institute for Brain Research
- Dongwei Li · correspondingBeijing Normal University; Chinese Institute for Brain Research; University of Birmingham
- Yuanjun KongBeijing Normal University; Chinese Institute for Brain Research
- Hongyu LiuThe University of Texas at Arlington; Beijing Normal University; Chinese Institute for Brain Research
- Yiqing HuBeijing Normal University; Chinese Institute for Brain Research
- Haijing NiuBeijing Normal University; Chinese Institute for Brain Research
Abstract
Transcranial photobiomodulation (tPBM) is a safe and noninvasive intervention that has shown promise for improving cognitive performance. Whether tPBM can modulate brain activity and thereby enhance working memory (WM) capacity in humans remains unclear. In this study, we found that 1064-nm tPBM applied to the right prefrontal cortex (PFC) improves visual working memory capacity and increases occipitoparietal contralateral delay activity (CDA). The CDA set-size effect during retention mediated the effect between the 1064-nm tPBM and subsequent WM capacity. The behavioral benefits and the corresponding changes in the CDA set-size effect were absent with tPBM at a wavelength of 852 nm or with stimulation of the left PFC. Our findings provide converging evidence that 1064-nm tPBM applied to the right PFC can improve WM capacity.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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