Egg Consumption, Cardiovascular Disease and Cardiometabolic Risk Factors: The Interaction with Saturated Fatty Acids. Results from the ATTICA Cohort Study (2002-2012)
Kouvari M, Damigou E, Florentin M, Kosti RI, Chrysohoou C, Pitsavos CS, Panagiotakos DB
Nutrients · 6 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Cohort study (indexed by PubMed)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Food frequency questionnaire
Who paid for it
- Funding
- Independent funding
- Nonprofit
- Hellenic Atherosclerosis Society
- Nonprofit
- Hellenic Society of Cardiology
- Nonprofit
- Hellenic Cardiology Society
- Grants
- Hellenic Atherosclerosis Society (HAS2003); Hellenic Atherosclerosis Society (HCS2002); Hellenic Society of Cardiology (HAS2003); Hellenic Society of Cardiology (HCS2002)
Based on 3 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2022-12-12 · Nutrients · vol. 14 · issue 24 · p. 5291
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 10 citations · more than 86% of similar papers · 1.9× the field average
- References
- 26 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Nutritional Studies and Diet · Diet and metabolism studies · Fatty Acid Research and Health
- Keywords
- Medicine, Cohort, Environmental health, Cohort study, Disease, Internal medicine, Physiology, Food science, Endocrinology, Biology
- MeSH
- humans, cardiovascular diseases, fatty acids, incidence, risk, risk factors, cohort studies, adolescent, adult, female, male
7 authors
From AU, GR
- Matina KouvariUniversity of Canberra; Harokopio University of Athens
- Evangelia DamigouHarokopio University of Athens
- Matilda Florentin · correspondingUniversity of Ioannina
- Rena I. KostiUniversity of Thessaly
- Christina A. ChrysohoouNational and Kapodistrian University of Athens
- Christos S. PitsavosNational and Kapodistrian University of Athens
Abstract
Purpose: To examine the association of egg intake with 10-year risk of cardiovascular disease (CVD) and other cardiometabolic risk factors in a sample of individuals of Mediterranean origin. Methods: In 2001−2002, n = 1514 men and n = 1528 women (>18 years old) from the greater Athens area, Greece, were enrolled. Information on any egg intake, eaten as a whole, partly or in recipes was assessed via a validated semi-quantitative food frequency questionnaire. Follow-up for CVD evaluation (2011−2012) was achieved in n = 2020 participants (n = 317 CVD cases). Results: Ranking from lowest (<1 serving/week) to intermediate (1−4 servings/week) and high (4−7 servings/week) egg consumption tertiles, lower CVD incidence was observed (18%, 9% and 8%, respectively, p-for-trend = 0.004). Unadjusted analysis revealed that 1−3 eggs/week and 4−7 eggs/week were associated with a 60% and 75%, respectively, lower risk of developing CVD compared with the reference group (<1 egg/week). When adjusting for sociodemographic, lifestyle and clinical factors, significance was retained only for 1−3 eggs/week (hazard ratio (HR) = 0.53, 95% confidence interval (95% CI) = 0.28, 1.00). When total saturated fatty acid (SFA) intake was taken into account, this inverse association was non-significant. Multi-adjusted analysis revealed that in participants of low SFA intake, 1 serving/day increase in egg intake resulted in 45% lower risk of developing CVD. In the case of higher SFA consumption, only 1−3 eggs/week seemed to protect against CVD (HR = 0.25, 95% CI = 0.07, 0.86). In the case of intermediate cardiometabolic disorders, no significant trend was observed. Conclusions: Overall dietary habits principally in terms of SFA intake may be detrimental to define the role of eggs in cardiac health.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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