Feasibility and acceptability of time-restricted eating in a group of adults with multiple sclerosis
Wingo BC, Rinker JR, Green K, Peterson CM
Frontiers in neurology · 18 citations
How it was studied
- Design
- Controlled clinical trial (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
- Government
- National Institutes of Health
- University or hospital
- Nutrition Obesity Research Center, University of Alabama at Birmingham
- Government
- National Institute of Diabetes and Digestive and Kidney Diseases
- Government
- NIDDK NIH HHS
- Grants
- Nutrition Obesity Research Center, University of Alabama at Birmingham (P30DK056336); National Institute of Diabetes and Digestive and Kidney Diseases (P30-DK-056336); National Institutes of Health (P30DK056336)
Based on 4 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2023-01-12 · Front Neurol · vol. 13 · p. 1087126
- Publisher
- Frontiers Media
- Cited
- 30 citations · more than 95% of similar papers · 4.1× the field average
- Impact
- Top 10% most cited in its field
- References
- 42 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Dietary Effects on Health · Genetics, Aging, and Longevity in Model Organisms · Multiple Sclerosis Research Studies
- Keywords
- Multiple sclerosis, Psychology, Medicine, Group (periodic table), Clinical psychology, Physical medicine and rehabilitation, Psychiatry
4 authors
From US
- Brooks C. Wingo · correspondingUniversity of Alabama at Birmingham
- John Robert RinkerUniversity of Alabama at Birmingham
- Kathryn E. GreenUniversity of Alabama at Birmingham
- Courtney M. PetersonUniversity of Alabama at Birmingham
Abstract
Introduction
Intermittent fasting (IF) has become a popular dietary pattern for adults with multiple sclerosis (MS), and initial studies in animal models and human trials indicate promising results for improving symptoms and slowing disease progression. Most studies published to date have focused on alternate day fasting or fasting mimicking diets including a 5:2 pattern, in which participants greatly restrict calorie intake on two non-consecutive days and eat regularly on other days; however, time restricted eating (TRE) may be equally effective for improving symptoms and may lead to better long term adherence due to its focus only on the time of day in which calories are consumed with no restriction on number of calories or types of food consumed.
Methods
The purpose of this pilot study was to determine the feasibility and acceptability of a TRE intervention in adults with relapsing remitting MS (RRMS). Participants (n = 12) were instructed to eat all food within an 8-h window every day and fast the remaining 16 h for 8 weeks.
Results
The eating pattern was determined to be feasible based on retention rates (n = 11; 92%) and acceptable based on participant feedback.
Discussion
Exploratory results of changes in cognition, pain, and fatigue, indicate that further study of TRE in this population is warranted.
Clinical trial registration
https://clinicaltrials.gov/ct2/show/NCT04389970; NCT04389970.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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