Cross-sectional study2023Industry fundedOpen access

Funded in part by Bega Dairy and Drinks Pty Ltd, Cobram Estate Pty. Ltd.

Ultra-Processed Food Consumption and Depressive Symptoms in a Mediterranean Cohort

Godos J, Bonaccio M, Al-Qahtani WH, Marx W, Lane MM, Leggio GM, Grosso G

Nutrients · 30 citations

Review labels

Author industry tiesFood frequency questionnaireIndustry funded

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Cross-sectional study (indexed by PubMed)
Studied in
People
Main outcome
Health markers and function
Intake measured by
Food frequency questionnaire

Who paid for it

Funding
Industry funded
Nonprofit
PA Research Foundation
University or hospital
La Trobe University
University or hospital
Deakin University
University or hospital
University of Queensland
Nonprofit
Nutrition Society of Australia
Nonprofit
Cancer Council Queensland
Company
Bega Dairy and Drinks Pty Ltd
Government
co-financing of the European Union—FSE-REACT-EU, PON Research and Innovation 2014–2020 DM1062/2021
Government
NHMRC Investigator Grant
Nonprofit
Princess Alexandra Research Foundation
Nonprofit
The Cancer Council Queensland
Nonprofit
Nutrition Research Australia and ParachuteBH
Company
Cobram Estate Pty. Ltd.
Government
Distinguished Scientist Fellowship Program
Authors
At least one author declares a financial tie to industry
Grants
PA Research Foundation (E65F21002560001); La Trobe University (E65F21002560001); University of Queensland (E65F21002560001); La Trobe University (#2008971); PA Research Foundation (#2008971); Deakin University (E65F21002560001); Cancer Council Queensland (#2008971); Nutrition Society of Australia (E65F21002560001); Nutrition Society of Australia (#2008971); University of Queensland (#2008971); Deakin University (#2008971); Cancer Council Queensland (E65F21002560001)

Based on 14 listed funder(s) and full-text disclosure statement.

Publication

Published
2023-01-18 · Nutrients · vol. 15 · issue 3 · p. 504
Publisher
Multidisciplinary Digital Publishing Institute
Cited
43 citations · more than 99% of similar papers · 10.0× the field average
Impact
Top 10% most cited in its field
References
60 works
Access
Open access (journal) · CC-BY
Research areas
Consumer Attitudes and Food Labeling · Nutritional Studies and Diet · Obesity, Physical Activity, Diet
Keywords
Mediterranean diet, Medicine, Odds ratio, Confounding, Confidence interval, Epidemiology, Quartile, Environmental health, Depression (economics), Demography, Odds, Cohort, Cohort study, Logistic regression, Gerontology, Internal medicine
MeSH
humans, diet, cross-sectional studies, depression, diet, mediterranean, food handling, adolescent, adult, young adult, fast foods, food, processed

7 authors

From IT, SA, AU

  • Justyna GodosUniversity of Catania
  • Marialaura BonaccioIstituto Neurologico Mediterraneo
  • Wahidah H. Al-QahtaniKing Saud University
  • Wolfgang MarxDeakin University
  • Melissa M. LaneDeakin University
  • Gian Marco LeggioUniversity of Catania

Abstract

Excess consumption of ultra-processed foods (UPFs) is currently under investigation for its potentially detrimental impact on human health. Current evidence demonstrates a substantial association with an increased risk of metabolic disorders, but data on mental health outcomes are just emerging. The aim of this study was to investigate the relationship between the consumption of UPFs and depressive symptoms in a sample of younger Italian adults. A cross-sectional study was conducted on 596 individuals (age 18-35 y) recruited in southern Italy. Food frequency questionnaires and the NOVA classification were used to assess dietary factors; the Center for the Epidemiological Studies of Depression Short Form (CES-D-10) was used to assess presence of depressive symptoms. Individuals in the highest quartile of UPF consumption had higher odds of having depressive symptoms in the energy-adjusted model (odds ratio (OR) = 1.89, 95% confidence interval (CI): 1.06, 3.28); the association remained significant after adjusting for potential confounding factors (OR = 2.04, 95% CI: 1.04, 4.01) and became even stronger after further adjustment for adherence to the Mediterranean diet as a proxy of diet quality (OR = 2.70, 95% CI: 1.32, 5.51). In conclusion, a positive association between UPF consumption and likelihood of having depressive symptoms was found in younger Italian individuals. Given the consistency of the findings after adjustment for diet quality, further studies are needed to understand whether non-nutritional factors may play a role in human neurobiology.

Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).

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