Cohort study2023Industry fundedOpen access

Funded in part by American Egg Board’s Egg Nutrition Center of the U.S. Department of Agriculture

Egg Intake Is Associated with Lower Risks of Impaired Fasting Glucose and High Blood Pressure in Framingham Offspring Study Adults

Mott MM, Zhou X, Bradlee ML, Singer MR, Yiannakou I, Moore LL

Nutrients · 6 citations

Review labels

Industry fundedNo stated lifestyle adjustment

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Cohort study (indexed by PubMed)
Studied in
People
Main outcome
Clinical events such as disease or death
Intake measured by
Food diaries or recalls

Who paid for it

Funding
Industry funded
Government
U.S. Department of Agriculture
Government
National Heart, Lung, and Blood Institute
Government
NHLBI NIH HHS
Industry group
American Egg Board’s Egg Nutrition Center of the U.S. Department of Agriculture
Grants
National Heart, Lung, and Blood Institute (HC25195); National Heart, Lung, and Blood Institute (N01‐HC25195); National Heart, Lung, and Blood Institute (HHSN268201500001I); National Heart, Lung, and Blood Institute (HHSN268201500001C); National Heart, Lung, and Blood Institute (N01-HC); National Heart, Lung, and Blood Institute (N01-HC-025195)

Based on 4 listed funder(s) and full-text disclosure statement.

Publication

Published
2023-01-18 · Nutrients · vol. 15 · issue 3 · p. 507
Publisher
Multidisciplinary Digital Publishing Institute
Cited
6 citations · more than 79% of similar papers · 1.4× the field average
References
54 works
Access
Open access (journal) · CC-BY
Research areas
Nutritional Studies and Diet · Obesity, Physical Activity, Diet · Consumer Attitudes and Food Labeling
Keywords
Medicine, Offspring, Blood pressure, Hazard ratio, Type 2 diabetes, Body mass index, Confounding, Framingham Heart Study, Diabetes mellitus, Proportional hazards model, Framingham Risk Score, Internal medicine, Impaired fasting glucose, Prospective cohort study, Lower risk, Physiology, Endocrinology, Impaired glucose tolerance, Confidence interval, Biology, Disease, Pregnancy
MeSH
humans, hypertension, diabetes mellitus, type 2, prediabetic state, blood glucose, diet, fasting, risk factors, prospective studies, blood pressure, eggs, adult

6 authors

From US

  • Melanie M. MottBoston University; EBSCO Industries (United States)
  • Xinyi ZhouBoston University
  • M. Loring BradleeBoston University
  • Martha R. SingerBoston University
  • Ioanna YiannakouBoston University
  • Lynn L. Moore · correspondingBoston University

Abstract

The association between egg consumption and cardiometabolic risk factors such as high blood pressure (HBP) and impaired fasting glucose (IFG) or type 2 diabetes (T2D) is still under debate. This study examines the association between egg consumption and these outcomes among 2349 30-64 year-old adults in the prospective Framingham Offspring Study. Diet was assessed using three-day dietary records. Potential confounders retained in the final models included age, sex, body mass index, and other dietary factors. The analysis of covariance and Cox proportional hazard's models were used to assess the relevant continuous (i.e., FG, SBP, DBP) and categorical (i.e., T2D, HBP) outcomes. Consuming ≥5 eggs per week was associated with lower mean FG (p = 0.0004) and SBP (p = 0.0284) after four years of follow-up. Higher egg intakes led to lower risks of developing IFG or T2D (HR: 0.72; 95% CI: 0.51-1.03) and high blood pressure (HBP) (HR: 0.68; 0.50-0.93). The beneficial effects of egg consumption were stronger in combination with other healthy dietary patterns. This study found that regular egg consumption as part of a healthy diet had long-term beneficial effects on blood pressure and glucose metabolism and lowered the long-term risks of high blood pressure and diabetes.

Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).

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