The effects of a single and a series of Finnish sauna sessions on the immune response and HSP-70 levels in trained and untrained men
Pilch W, Szarek M, Olga CL, Anna P, Żychowska M, Ewa SK, Andraščíková Š, Pałka T
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 4 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Controlled clinical trial (classified by our AI screen)
- Studied in
- People
- Main outcome
- Mechanisms only
Who paid for it
- Funding
- Independent funding
- University or hospital
- Akademia Wychowania Fizycznego im. Bronisława Czecha w Krakowie
Based on 1 listed funder(s).
Publication
- Published
- 2023-02-22 · Int J Hyperthermia · vol. 40 · issue 1 · p. 2179672
- Publisher
- Taylor & Francis
- Cited
- 10 citations · more than 76% of similar papers · 1.0× the field average
- References
- 44 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Exercise and Physiological Responses · Thermoregulation and physiological responses · Therapeutic Uses of Natural Elements
- Keywords
- Medicine, Immune system, White blood cell, Hyperthermia, Lymphocyte, Immunology, Internal medicine, Anthropometry, Physiology, Endocrinology
- MeSH
- humans, hydrocortisone, immunoglobulin a, immunoglobulin g, immunoglobulin m, interleukin-6, interleukin-10, body temperature, steam bath, immunity, adult, male, hsp70 heat-shock proteins, young adult
8 authors
From PL, SK
- Wanda PilchUniversity of Physical Culture in Kraków
- Marta SzarekMinistry of Interior and Administration
- Olga Czerwińska‐Ledwig · correspondingUniversity of Physical Culture in Kraków
- Anna PiotrowskaUniversity of Physical Culture in Kraków
- Małgorzata ŻychowskaKazimierz Wielki University in Bydgoszcz
- Ewa Sadowska‐KrępaAkademii Wychowania Fizycznego im. Jerzego Kukuczki w Katowicach
Abstract
Background
The aim of the study was to investigate the effect of a Finnish sauna on the immune status parameters. The hypothesis was that hyperthermia would improve immune system's functioning by changing the proportion of lymphocyte subpopulations and would activate heat shock proteins. We assumed that the responses of trained and untrained subjects would be different.
Material and methods
Healthy men (20-25 years old) were divided into groups: the trained (T; n = 10), and the untrained group (U; n = 10). All participants were subjected to 10 baths (each one consisted of: 3 × 15-minute exposure with cooled down for 2 min. Body composition, anthropometric measurements, VO2 peak were measured before 1st sauna bath. Blood was collected before the 1st and 10th sauna bath, and 10 min after their completion to asses an acute and a chronic effect. Body mass, rectal temperature and heart rate (HR) were assessed in the same time points. The serum levels of cortisol, Il-6, HSP70 were measured with use of ELISA method, IgA, IgG and IgM by turbidimetry. White blood cells (WBC), leukocyte populations counts: neutrophils, lymphocytes, eosinophils, monocytes, and basophils were determined with use of flow cytometry as well as T-cell subpopulations.
Results
No differences were found in the increase in rectal temperature, cortisol and immunoglobulins between groups. In response to the 1st sauna bath, a greater increase in HR was observed in the U group. After the last one, the HR value was lower in the T group. The impact of sauna baths on WBC, CD56+, CD3+, CD8+, IgA, IgG and IgM was different in trained and untrained subjects' responses. A positive correlation between the increase in cortisol concentrations and increase in internal temperatures after the 1st sauna was found in the T (r = 0.72) and U group (r = 0.77), between the increase in IL-6 and cortisol concentrations in the T group after the 1st treatment (r = 0.64), between the increase in IL-10 concentration and internal temperature (r = 0.75) and between the increase in IL-6 and IL-10 (r = 0.69) concentrations, also.
Conclusions
Sauna bathing can be a way to improve the immune response, but only when it is undertaken as a series of treatments.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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