The Impact of Whole-Body Cryotherapy on Endothelium Parameters in Patients with Ankylosing Spondylitis
Stanek A, Romuk E, Wielkoszyński T, Brożyna-Tkaczyk K, Wziątek-Kuczmik D, Cholewka A
Antioxidants (Basel, Switzerland) · 3 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Controlled clinical trial (classified by our AI screen)
- Studied in
- People
- Main outcome
- Mechanisms only
Who paid for it
- Funding
- Independent funding
- University or hospital
- Medical University of Silesia
Based on 1 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2023-02-19 · Antioxidants (Basel) · vol. 12 · issue 2 · p. 521
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 12 citations · more than 79% of similar papers · 1.3× the field average
- References
- 55 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Exercise and Physiological Responses · Spondyloarthritis Studies and Treatments · Therapeutic Uses of Natural Elements
- Keywords
- Ankylosing spondylitis, Cryotherapy, Medicine, Physical therapy, Surgery
6 authors
From PL
- Agata Stanek · correspondingMedical University of Silesia
- Ewa Barbara RomukMedical University of Silesia
- Tomasz WielkoszyńskiWyższa Szkoła Planowania Strategicznego
- Klaudia Brożyna-TkaczykMedical University of Lublin
- Daria Wziątek-KuczmikMedical University of Silesia
- Armand CholewkaUniversity of Silesia in Katowice
Abstract
Background
The aim of the study was to assess the effect of whole-body cryotherapy (WBC) with subsequent exercise training (WBC group) or exercise-only training (ET group) on endothelium inflammation parameters in patients with ankylosing spondylitis (AS).
Methods
The WBC procedure lasted 3 min, and exercise training consisted of one 60 min session a day, which was the same in each group. The ET group was compared to the WBC group. Endothelium (high-sensitivity C-reactive protein (hsCRP), soluble P-Selectin, soluble vascular cell adhesion molecule-1 (sVCAM-1), neopterin), and oxidative stress (lipid hydroperoxide (LHP), protein sulfhydryl (PSH), lipofuscin, paraoxonase-1(PON-1), and albumin) parameters were estimated 1 day before and 1 day after the completion of the study.
Results
A significant decrease in hsCRP, sP-Selectin, sVCAM-1, and neopterin concentrations was observed in the WBC group after the treatment. After the treatment, in both groups, LHP and lipofuscin levels and PON-1 activity decreased significantly. The observed drop in these parameters was higher in the WBC group compared to the ET group. Albumin concentration increased in the WBC group after treatment.
Conclusion
Procedures of WBC have a beneficial effect on endothelium parameters in AS patients; therefore, this method can be applied in the treatment of this group of patients.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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