The effect of caffeine on subsequent sleep: A systematic review and meta-analysis
Gardiner C, Weakley J, Burke LM, Roach GD, Sargent C, Maniar N, Townshend A, Halson SL
Sleep medicine reviews · 131 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Meta-analysis (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2023-02-06 · Sleep Med Rev · vol. 69 · p. 101764
- Publisher
- Elsevier BV
- Cited
- 308 citations · more than 100% of similar papers · 14.8× the field average
- Impact
- Top 10% most cited in its field
- References
- 91 works
- Access
- Open access (hybrid journal) · CC-BY
- Research areas
- Sleep and related disorders · Coffee research and impacts · Sleep and Work-Related Fatigue
- Keywords
- Caffeine, Bedtime, Sleep (system call), Meta-analysis, Sleep onset latency, Sleep onset, Medicine, Anesthesia, Psychology, Internal medicine, Psychiatry, Insomnia
- MeSH
- humans, sleep deprivation, caffeine, polysomnography, sleep, coffee
8 authors
From AU, GB
- Carissa GardinerAustralian Catholic University
- Jonathon J. S. Weakley · correspondingLeeds Beckett University; Australian Catholic University
- Louise M. BurkeAustralian Catholic University
- Gregory Daniel RoachCentral Queensland University
- Charli SargentCentral Queensland University
- Nirav ManiarAustralian Catholic University
Abstract
The consumption of caffeine in response to insufficient sleep may impair the onset and maintenance of subsequent sleep. This systematic review and meta-analysis investigated the effect of caffeine on the characteristics of night-time sleep, with the intent to identify the time after which caffeine should not be consumed prior to bedtime. A systematic search of the literature was undertaken with 24 studies included in the analysis. Caffeine consumption reduced total sleep time by 45 min and sleep efficiency by 7%, with an increase in sleep onset latency of 9 min and wake after sleep onset of 12 min. Duration (+6.1 min) and proportion (+1.7%) of light sleep (N1) increased with caffeine intake and the duration (-11.4 min) and proportion (-1.4%) of deep sleep (N3 and N4) decreased with caffeine intake. To avoid reductions in total sleep time, coffee (107 mg per 250 mL) should be consumed at least 8.8 h prior to bedtime and a standard serve of pre-workout supplement (217.5 mg) should be consumed at least 13.2 h prior to bedtime. The results of the present study provide evidence-based guidance for the appropriate consumption of caffeine to mitigate the deleterious effects on sleep.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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