Health effects of the time-restricted eating in adults with obesity: A systematic review and meta-analysis
Chen W, Liu X, Bao L, Yang P, Zhou H
Frontiers in nutrition · 32 citations
How it was studied
- Design
- Systematic review (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
Based on full-text disclosure statement.
Publication
- Published
- 2023-02-16 · Front Nutr · vol. 10 · p. 1079250
- Publisher
- Frontiers Media
- Cited
- 44 citations · more than 89% of similar papers · 2.2× the field average
- References
- 53 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Dietary Effects on Health · Circadian rhythm and melatonin · Enhanced Recovery After Surgery
- Keywords
- Overweight, Medicine, Body mass index, Waist, Meta-analysis, Insulin resistance, Obesity, Blood pressure, Internal medicine, Randomized controlled trial, Weight loss, Endocrinology, Physical therapy
5 authors
From CN
- Wei‐Yi ChenQingdao University; Yuhuangding Hospital
- Xiaoli LiuPeople’s Hospital of Rizhao
- Lei BaoQingdao University; Yuhuangding Hospital
- Ping YangQingdao University; Yuhuangding Hospital
- Huihui Zhou · correspondingQingdao University; Yuhuangding Hospital
Abstract
Background
The number of people suffering from overweight or obesity has been steadily increasing in recent years. As a new form of diet, the efficacy of time-restricted eating (TRE) remains debatable.
Objective
This meta-analysis quantified the effect of TRE on weight change and other physical parameters in obese and overweight adults.
Methods
We did a systematic review and meta-analysis of randomized controlled trials (RCTs) comparing the TRE interventions on weight loss and other metabolic parameters by searching PubMed, Embase, and Cochrane Central Register of Controlled Trials to identify eligible trials published from database inception up until 23 August 2022. The risk of bias was assessed using the Revised Cochrane risk-of-bias tool (ROB-2.0). Meta-analysis was performed using Review Manager 5.4.1 software.
Results
Nine RCTs with 665 individuals (345 in the TRE group while 320 in the control group) were included. Results indicated that TRE had a greater decrease in body weight (-1.28 kg; 95% CI [-2.05, -0.52], p = 0.001), fat mass (-0.72 kg; 95% CI [-1.40, -0.03], p = 0.04), body mass index (-0.34 kg/m2; 95% CI [-0.64, -0.04], p = 0.03) and diastolic blood pressure (-2.26 mmHg 95% CI [-4.02, -0.50], p = 0.01). However, the meta-analysis demonstrated that there was no significant difference between TRE and the control group in lean mass, systolic blood pressure, waist circumference, fasting glucose, fasting insulin, homeostasis model assessment-insulin resistance (HOMA-IR), total cholesterol, high-density lipoprotein, low-density lipoprotein, and triglycerides. Besides, the duration of the study and daily eating window also had an impact on weight change.
Conclusion
TRE was associated with reductions in weight and fat mass and can be a dietary intervention option for adults with obesity. But high-quality trials and longer follow-ups are needed to draw definitive conclusions.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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