Funded in part by Kaken Pharmaceutical
The Global Association between Egg Intake and the Incidence and Mortality of Ischemic Heart Disease-An Ecological Study
Sugihara N, Shirai Y, Imai T, Sezaki A, Abe C, Kawase F, Miyamoto K, Inden A, Kato T, Sanada M, Shimokata H
International journal of environmental research and public health · 5 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Cross-sectional study (classified by our AI screen)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Not stated
Who paid for it
- Funding
- Industry funded
- Company
- Kaken Pharmaceutical
- Government
- Japan Society for the Promotion of Science
- Government
- JSPS KAKENHI
- Grants
- Japan Society for the Promotion of Science (17K12912); Kaken Pharmaceutical (JP 17K12912)
Based on 3 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2023-02-25 · Int J Environ Res Public Health · vol. 20 · issue 5 · p. 4138
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 3 citations · more than 69% of similar papers · 0.7× the field average
- References
- 33 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Nutritional Studies and Diet · Obesity, Physical Activity, Diet · Consumer Attitudes and Food Labeling
- Keywords
- Ecological study, Incidence (geometry), Per capita, Demography, Disease, Medicine, Consumption (sociology), Environmental health, Population, Internal medicine
- MeSH
- humans, myocardial ischemia, diet, incidence, linear models, eggs
11 authors
From JP
- Norie Sugihara · correspondingOchanomizu University; Kanagawa University of Human Services
- Yoshiro ShiraiKinjo Gakuin University; Nagoya University of Arts and Sciences
- Tomoko ImaiDoshisha Women's College of Liberal Arts; Nagoya University of Arts and Sciences
- Ayako SezakiRyukoku University; Nagoya University of Arts and Sciences
- Chisato AbeTsu City College; Nagoya University of Arts and Sciences
- Fumiya KawaseNagoya University of Arts and Sciences
Abstract
The relationship between egg consumption and ischemic heart disease (IHD) remains controversial as there is still no clear answer regarding the relationship, with research limited to a few geographical regions. In the current study, we conducted a longitudinal analysis of the association between egg intake and IHD incidence (IHDi) and mortality (IHDd) using 28 years of international data from 1990 to 2018. Egg intake (g/day/capita) by country was obtained from the Global Dietary Database. Age-standard IHDi and IHDd rates per 100,000 subjects in each country were obtained from the 2019 Global Burden of Disease database. The analysis included a total of 142 countries with populations of at least one million, for which all data were available from 1990 to 2018. Eggs are consumed worldwide, and regional differences in consumption are also shown. Utilizing IHDi and IHDd as objective variables and egg intake as an explanatory variable, the analysis was conducted using linear mixed models, which controlled for inter- and intra-country variation from year to year. The results showed a significant negative association between egg intake, and IHDi (-0.253 ± 0.117, p p < 0.05). The analysis was carried out using R 4.0.5. The results suggest that adequate egg intake might suppress IHDi and IHDd on a global scale.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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