Association between magnesium intake and the risk of anemia among adults in the United States
Huang J, Xu J, Ye P, Xin X
Frontiers in nutrition · 11 citations
How it was studied
- Design
- Cross-sectional study (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
Based on full-text disclosure statement.
Publication
- Published
- 2023-02-23 · Front Nutr · vol. 10 · p. 1046749
- Publisher
- Frontiers Media
- Cited
- 12 citations · more than 79% of similar papers · 1.5× the field average
- References
- 51 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Magnesium in Health and Disease · Parathyroid Disorders and Treatments · Iron Metabolism and Disorders
- Keywords
- Medicine, Anemia, Odds ratio, National Health and Nutrition Examination Survey, Magnesium deficiency (plants), Magnesium, Quartile, Confidence interval, Epidemiology, Prospective cohort study, Internal medicine, Environmental health, Population
4 authors
From CN
- Jungao HuangGansu Provincial Maternal and Child Health Hospital
- Jing XuGanzhou People's Hospital
- Ping YeGanzhou People's Hospital
- Xiaoqin Xin · correspondingGanzhou People's Hospital
Abstract
Background
Magnesium deficiency is related to an increased risk of anemia, but epidemiological evidence supporting this association remains scarce. The purpose of the present survey was to evaluate the relationship between dietary magnesium intake and the risk of anemia.
Methods
In total, 13,423 participants aged 20-80 years were enrolled using data from the National Health and Nutrition Examination Survey 2011-2016. Magnesium consumption was evaluated using 24 h dietary recalls. Multivariable generalized linear models were developed to demonstrate the association between dietary magnesium intake and the prevalence of anemia.
Results
An inverse association between dietary magnesium intake and the risk of anemia was detected based on a full adjustment model. We evaluated magnesium intake as a categorical variable (five quartiles). Compared with the lowest value, the highest multivariate adjusted odds ratio (95% confidence interval) for anemia was 0.64 (0.46-0.89). Stratified analyses revealed a reverse relationship between magnesium intake and anemia in women. However, no significant association was observed in men (p for trend = 0.376). A similar reverse association was found among the older group (aged ≥60 years).
Conclusion
Magnesium deficiency is closely related to a higher rate of anemia occurrence, especially among women and older Americans. Further larger-scale prospective studies are required to confirm these conclusions.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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