Alternate-Day Fasting Combined with Exercise: Effect on Sleep in Adults with Obesity and NAFLD
Ezpeleta M, Gabel K, Cienfuegos S, Kalam F, Lin S, Pavlou V, Varady KA
Nutrients · 22 citations
How it was studied
- Design
- Randomized controlled trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
- Government
- National Institutes of Health
- Government
- National Cancer Institute
- Government
- National Institute of Diabetes and Digestive and Kidney Diseases
- Government
- NIH HHS
- Government
- NCI NIH HHS
- Government
- NIDDK NIH HHS
- Grants
- National Cancer Institute (#T32CA193193); National Institute of Diabetes and Digestive and Kidney Diseases (R01DK119783); National Institutes of Health (R01 DK119783)
Based on 6 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2023-03-14 · Nutrients · vol. 15 · issue 6 · p. 1398
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 27 citations · more than 94% of similar papers · 3.7× the field average
- Impact
- Top 10% most cited in its field
- References
- 27 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Dietary Effects on Health · Liver Disease Diagnosis and Treatment · Diet and metabolism studies
- Keywords
- Medicine, Bedtime, Obesity, Internal medicine, Aerobic exercise, Physical therapy, Weight loss, Endocrinology
- MeSH
- humans, sleep apnea, obstructive, sleep initiation and maintenance disorders, obesity, body weight, triglycerides, exercise, fasting, sleep, adult, non-alcoholic fatty liver disease
7 authors
From US
- Mark EzpeletaUniversity of Illinois Chicago
- Kelsey GabelUniversity of Illinois Chicago
- Sofia CienfuegosUniversity of Illinois Chicago
- Faiza KalamUniversity of Illinois Chicago
- Shuhao LinUniversity of Illinois Chicago
- Vasiliki PavlouUniversity of Illinois Chicago
Abstract
Objective: This study investigated how alternate-day fasting (ADF) combined with aerobic exercise impacts body weight and sleep in adults with non-alcoholic fatty liver disease (NAFLD). Methods: Adults with obesity and NAFLD (n = 80) were randomized into one of four groups for 3 months: combination of ADF (600 kcal "fast day," alternated with an ad libitum intake "feast day") and moderate-intensity aerobic exercise (five sessions per week, 60 min/session); ADF alone; exercise alone; or a no-intervention control group. Results: By month 3, body weight and intrahepatic triglyceride content decreased (p Conclusions: The weight loss induced by ADF combined with exercise does not improve sleep quality, duration, insomnia severity, or risk of obstructive sleep apnea in individuals with NAFLD.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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