Efficacy of Photobiomodulation Therapy in the Treatment of Pain and Inflammation: A Literature Review
González-Muñoz A, Cuevas-Cervera M, Pérez-Montilla JJ, Aguilar-Núñez D, Hamed-Hamed D, Aguilar-García M, Pruimboom L, Navarro-Ledesma S
Healthcare (Basel, Switzerland) · 32 citations
How it was studied
- Design
- Systematic review (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
- University or hospital
- Universidad de Granada
- University or hospital
- University Chair in Clinical Psychoneuroimmunology (University of Granada and PNI Europe)
Based on 2 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2023-03-24 · Healthcare (Basel) · vol. 11 · issue 7 · p. 938
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 61 citations · more than 99% of similar papers · 9.2× the field average
- Impact
- Top 10% most cited in its field
- References
- 40 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Laser Applications in Dentistry and Medicine · Pain Management and Treatment · Pain Mechanisms and Treatments
- Keywords
- Medicine, Inflammation, Intensive care medicine, Internal medicine
8 authors
From ES
- Ana González-MuñozUniversidad de Granada
- María Cuevas-CerveraUniversidad de Granada
- José Javier Pérez‐MontillaUniversidad de Granada
- Daniel Aguilar-NúñezUniversidad de Málaga
- Dina Hamed‐HamedUniversidad de Granada
- María Aguilar-GarcíaUniversidad de Granada
Abstract
The main objective of this literature review was to analyze the efficacy of (PBM) therapy application on subjects with chronic pain and inflammation, and furthermore, to evaluate the methodological quality of the collected literature. The search was conducted using five databases: PubMed, ProQuest, Scopus, Web of Science, and PEDro. The keywords "low level laser therapy", "chronic pain", and "inflammation" provided the selection of RCTs that were published within the last 5 years, conducted in humans, and written in English. The PEDro Internal Validity Scale (IVS) checklist was used to evaluate the risk of bias in the included studies. A total of 11 articles were selected, all of them RCTs. Of the articles, five showed that PBM positively influences chronic pain, while another showed the same but only in the short term. In two other articles, the patient's inflammation improved markedly. In one article there was no improvement in chronic pain and in another, there was no improvement in inflammation. Four articles demonstrated that PBM is beneficial in acute pain. Furthermore, six studies were given an "excellent" score and the remaining five a "good" score based on the IVS. Photobiomodulation has beneficial effects on chronic pain and inflammation, although more research needs to be completed in this line for this to be clarified as the existence of RCTs on this subject is limited.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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