Effect of modified alternate day fasting diet on the severity of premenstrual syndrome and health-related quality of life in women with overweight or obesity: a trial study protocol
Hooshiar SH, Yazdani A, Jafarnejad S
BMJ open · 3 citations
How it was studied
- Design
- Randomized controlled trial (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
- University or hospital
- Kashan University of Medical Sciences
- Grants
- Kashan University of Medical Sciences (400174)
Based on 1 listed funder(s).
Publication
- Published
- 2023-05-01 · BMJ Open · vol. 13 · issue 5 · p. e066740
- Publisher
- BMJ
- Cited
- 5 citations · more than 77% of similar papers · 1.2× the field average
- References
- 49 works
- Access
- Open access (journal) · CC-BY-NC
- Research areas
- Menstrual Health and Disorders · Dietary Effects on Health · Menopause: Health Impacts and Treatments
- Keywords
- Medicine, Overweight, Body mass index, Waist, Obesity, Anthropometry, Quality of life (healthcare), Randomized controlled trial, Weight loss, Intermittent fasting, Physical therapy, Calorie restriction, Internal medicine
- MeSH
- humans, obesity, premenstrual syndrome, fasting, quality of life, adolescent, female, overweight, randomized controlled trials as topic
3 authors
From IR
- Saeedeh Hosseini HooshiarKashan University of Medical Sciences
- Akram YazdaniKashan University of Medical Sciences
- Sadegh Jafarnejad · correspondingKashan University of Medical Sciences
Abstract
Introduction
Premenstrual syndrome (PMS) includes a range of physical, behavioural and psychological symptoms and decreases women's health-related quality of life (HRQoL). It has been proposed that increased body mass index (BMI) is associated with menstrual problems and decreased HRQoL. The body fat amount plays a role in menstrual cycles by altering the oestrogen/progesterone ratio. Alternate day fasting as an unusual diet results in the improvement of anthropometric indices and reduction of body weight. This study aims to investigate the effect of a daily calorie restriction diet and a modified alternate day fasting diet on PMS and HRQoL.
Methods and analysis
This 8-week open-label parallel randomised controlled trial examines the impact of a modified alternate-day fasting diet and daily caloric restriction on the severity of PMS and HRQoL in obese or overweight women. Using simple random sampling, women between the ages of 18 years and 50 years and 25 ≤ BMI ˂ 40 who meet the inclusion and exclusion criteria will be chosen from the Kashan University of Medical Sciences Centre. Patients will be randomised, based on BMI and age through stratified randomisation. Then by the random numbers table, they are allocated to fasting (intervention) or daily calorie restriction (control) groups. Outcomes are chosen for the trial: the difference in the severity of PMS, HRQoL, BMI, body fat mass, fat-free mass, waist-to-hip ratio, waist circumference, hip circumference, per cent body fat, skeletal muscle mass and visceral fat area from baseline to 8 weeks.
Ethics and dissemination
The Kashan University of Medical Sciences Ethics Committee has approved the trial (IR.KAUMS.MEDNT.REC.1401.003) (17 April 2022). Results will be published in peer-reviewed academic journals and the participants will be informed via phone calls.
Trial registration number
IRCT20220522054958N1.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY-NC).
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