Effect of Nut Consumption on Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis
Pan L, Sui J, Xu Y, Zhao Q
Nutrients · 11 citations
How it was studied
- Design
- Meta-analysis (indexed by PubMed)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Not stated
Who paid for it
- Funding
- Independent funding
- Government
- China Postdoctoral Science Foundation
- Government
- China Postdoctoral Science Foundation funded project
- Government
- Innovation and Entrepreneurship Program of Jiangsu Province
Based on 3 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2023-05-19 · Nutrients · vol. 15 · issue 10 · p. 2394
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 13 citations · more than 63% of similar papers · 0.9× the field average
- References
- 75 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Nuts composition and effects · Nutritional Studies and Diet · Antioxidant Activity and Oxidative Stress
- Keywords
- Nonalcoholic fatty liver disease, Meta-analysis, Medicine, Nut, Odds ratio, Fatty liver, Internal medicine, Subgroup analysis, Epidemiology, Observational study, Cohort study, Confounding, Prospective cohort study, Environmental health, Disease
- MeSH
- humans, nuts, diet, prospective studies, cross-sectional studies, female, non-alcoholic fatty liver disease, observational studies as topic
4 authors
From CN
- Ling PanNanjing University of Information Science and Technology
- Jing Sui · correspondingNanjing University of Information Science and Technology; Southeast University
- Ying Jun XuNanjing University of Information Science and Technology
- Qun ZhaoNanjing University of Information Science and Technology
Abstract
Although previous epidemiological studies have been conducted to investigate the relationship between nut consumption and the risk of nonalcoholic fatty liver disease (NAFLD), the evidence remains inconclusive and contentious. The aim of our study was to further conduct a meta-analysis of observational studies to explore the latest evidence of the influence of nut consumption on NAFLD. This meta-analysis included a comprehensive search of all articles published in the PubMed and Web of Science online databases as of April 2023. A total of 11 articles were included, comprising 2 prospective cohort studies, 3 cross-sectional studies, and 7 case-control studies, and a random effects model was used to evaluate the relationship between nuts and NAFLD. Results showed that the odds ratio (OR) of NAFLD was 0.90 (95% CI: 0.81-0.99, p I2 = 76.2%). In summary, our findings provide support for a protective relationship between nut intake and risk of NAFLD. Further exploration of the association between other dietary components and NAFLD is an important avenue for future research.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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