Inflammatory markers may mediate the relationship between processed meat consumption and metabolic unhealthy obesity in women: a cross sectional study
Mohamadi A, Shiraseb F, Mirzababaei A, Barekzai AM, Clark CCT, Aali Y, Mirzaei K
Scientific reports · 3 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Cross-sectional study (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Food frequency questionnaire
Who paid for it
- Funding
- Independent funding
- University or hospital
- Tehran University of Medical Sciences and Health Services
Based on 1 listed funder(s).
Publication
- Published
- 2023-06-07 · Sci Rep · vol. 13 · issue 1 · p. 9261
- Publisher
- Nature Portfolio
- Cited
- 6 citations · more than 80% of similar papers · 1.4× the field average
- References
- 62 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Nutritional Studies and Diet · Adipokines, Inflammation, and Metabolic Diseases · Diet and metabolism studies
- Keywords
- Obesity, Cross-sectional study, Overweight, Anthropometry, Medicine, Body mass index, Odds ratio, Phenotype, Food frequency questionnaire, Internal medicine, Physiology, Environmental health, Biology, Pathology, Gene, Genetics
- MeSH
- humans, obesity, body mass index, cross-sectional studies, phenotype, meat, iran, female, transforming growth factor beta1, obesity, metabolically benign
7 authors
From IR, AF, GB
- Azam MohamadiTehran University of Medical Sciences
- Farideh ShirasebTehran University of Medical Sciences
- Atieh Mirzababaei · correspondingTehran University of Medical Sciences
- Ahmad Mujtaba BarekzaiKabul University; Kabul Education University; World Health Organization - Afghanistan; Spinghar Institute of Higher Education, Kabul
- Cain C. T. ClarkCoventry University
- Yasaman AaliTehran University of Medical Sciences
Abstract
Metabolically healthy obesity (MHO) and metabolically unhealthy obesity (MUHO) are known to be affected by diet and inflammatory factors (such as TGF-β1, IL-β1, MCP1). We sought to survey that consume of processed meat could effect on MHO and MUHO phenotypes, mediated through inflammatory markers, in overweight and obese Iranian women. The current cross-sectional study was done on 224 women 18-48 years, with a body mass index (BMI) ≥ 25 kg/m2. A 147- item food frequency questionnaire (FFQ) was used to evaluate dietary intake. In all participants, anthropometric indices and biochemical factors, as well as metabolic health phenotypes based on Karelis score, were evaluated. According to results, 22.6% of participants had MHO and 75.7% had MUHO phenotypes. There was an association between higher adherence to processed meats and increasing odds of MUHO phenotype in Iranian women (OR:2.54; 95% CI 0.009, 7.51; P = 0.05). Moreover, we found that the relation can be affected by agents such as TGF-β1, IL-β1, and MCP1; however, more research is needed to confirm these results and finding.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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