Systematic review2023Open access

Ultra-Processed Food Consumption and Incidence of Obesity and Cardiometabolic Risk Factors in Adults: A Systematic Review of Prospective Studies

Mambrini SP, Menichetti F, Ravella S, Pellizzari M, De Amicis R, Foppiani A, Battezzati A, Bertoli S, Leone A

Nutrients · 79 citations

How it was studied

Design
Systematic review (indexed by PubMed)
Studied in
People
Main outcome
Clinical events such as disease or death
Intake measured by
Not stated

Who paid for it

Funding
Independent funding

Based on full-text disclosure statement.

Publication

Published
2023-05-31 · Nutrients · vol. 15 · issue 11 · p. 2583
Publisher
Multidisciplinary Digital Publishing Institute
Cited
111 citations · more than 99% of similar papers · 7.1× the field average
Impact
Top 10% most cited in its field
References
63 works
Access
Open access (journal) · CC-BY
Research areas
Consumer Attitudes and Food Labeling · Nutritional Studies and Diet · Obesity, Physical Activity, Diet
Keywords
Environmental health, Obesity, Incidence (geometry), Medicine, Prospective cohort study, Consumption (sociology), Internal medicine
MeSH
humans, hypertension, obesity, diet, incidence, prospective studies, food handling, adult, obesity, abdominal, fast foods, cardiometabolic risk factors, food, processed

9 authors

From IT

  • Sara Paola MambriniUniversity of Milan; Ospedale San Giuseppe
  • Francesca MenichettiUniversity of Milan
  • Simone RavellaUniversity of Milan
  • Marta PellizzariIstituti di Ricovero e Cura a Carattere Scientifico
  • Ramona Silvana De AmicisUniversity of Milan; Istituti di Ricovero e Cura a Carattere Scientifico
  • Andrea FoppianiUniversity of Milan

Abstract

Ultra-processed foods (UPF) are energy-dense, nutritionally unbalanced products, low in fiber but high in saturated fat, salt, and sugar. Recently, UPF consumption has increased likewise the incidence of obesity and cardiometabolic diseases. To highlight a possible relationship, we conducted a systematic review of prospective studies from PubMed and Web of Science investigating the association between UPF consumption and the incidence of obesity and cardiometabolic risk factors. Seventeen studies were selected. Eight evaluated the incidence of general and abdominal obesity, one the incidence of impaired fasting blood glucose, four the incidence of diabetes, two the incidence of dyslipidemia, and only one the incidence of metabolic syndrome. Studies' quality was assessed according to the Critical Appraisal Checklist for cohort studies proposed by the Joanna Briggs Institute. Substantial agreement emerged among the studies in defining UPF consumption as being associated with the incident risk of general and abdominal obesity. More limited was the evidence on cardiometabolic risk. Nevertheless, most studies reported that UPF consumption as being associated with an increased risk of hypertension, diabetes, and dyslipidemia. In conclusion, evidence supports the existence of a relationship between UPF consumption and the incidence of obesity and cardiometabolic risk. However, further longitudinal studies considering diet quality and changes over time are needed.

Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).

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