Cruciferous Vegetable Intake and Risk of Prostate Cancer: A Systematic Review and Meta-Analysis
Long J, Liu Z, Liang S, Chen B
Urologia internationalis · 9 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Meta-analysis (indexed by PubMed)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Not stated
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2023-01-01 · Urol Int · vol. 107 · issue 7 · pp. 723–733
- Publisher
- Karger Publishers
- Cited
- 11 citations · more than 46% of similar papers · 0.3× the field average
- References
- 44 works
- Access
- Free to read
- Research areas
- Genomics, phytochemicals, and oxidative stress · Glutathione Transferases and Polymorphisms · Sulfur Compounds in Biology
- Keywords
- Cruciferous vegetables, Medicine, Confidence interval, Prostate cancer, Meta-analysis, Relative risk, Cochrane Library, Cohort study, Internal medicine, Cancer, Environmental health
- MeSH
- humans, brassicaceae, vegetables, prostatic neoplasms, diet, risk, risk factors, male
4 authors
From CN
- Jiaye LongInner Mongolia University
- Zhaohui LiuInner Mongolia University
- Shuai LiangInner Mongolia University
- Baoxiang ChenInner Mongolia University
Abstract
Introduction
The relationship between cruciferous vegetables and prostate cancer (PCa) risk remains contentious. This study aimed to assess the association between consuming cruciferous vegetables and PCa risk.
Methods
We carried out a systematic search through PubMed, Embase, Web of Science, and the Cochrane Library until September 20, 2022. The results of the article will be analyzed using the Stata 14 software. This meta-analysis was reported as directed by the PRISMA guidance, and the study protocol was recorded in PROSPERO (CRD42022361556).
Results
7 case-control studies and 9 cohort studies were eventually included, including 70,201 PCa cases and 1,264,437 members. The higher the intake of cruciferous vegetables, the lower the risk of PCa. In comparison to the lowest dose of cruciferous vegetables, the overall relative risk (RR) of cruciferous vegetables having the highest dose was 0.87 (95% confidence interval [CI]: 0.80-0.95; I2 = 59.2%). A significant linear trend (p = 0.002) was observed for the association, with a combined RR of 0.955 (95% CI: 0.928-0.982) for every 15 g of cruciferous vegetables per day.
Conclusions
The study revealed that consumption of cruciferous vegetables may be linked to reduced PCa risk.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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