Study2023Open access

Reverse skin aging signs by red light photobiomodulation

Couturaud V, Le Fur M, Pelletier M, Granotier F

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 25 citations

Review labels

Author industry ties

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Controlled clinical trial (classified by our AI screen)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Independent funding
Authors
At least one author declares a financial tie to industry

Based on full-text disclosure statement.

Publication

Published
2023-06-30 · Skin Res Technol · vol. 29 · issue 7 · p. e13391
Publisher
Wiley
Cited
50 citations · more than 98% of similar papers · 7.5× the field average
Impact
Top 10% most cited in its field
References
18 works
Access
Open access (hybrid journal) · CC-BY-NC-ND
Research areas
Laser Applications in Dentistry and Medicine · Dermatologic Treatments and Research · Photodynamic Therapy Research Studies
Keywords
Skin Aging, Wrinkle, Light-emitting diode, Intense pulsed light, Medicine, Cheek, Biomedical engineering, Dermis, Dermatology, Materials science, Surgery, Pathology, Optoelectronics
MeSH
face, skin, humans, aging, skin aging, light, female, low-level light therapy

4 authors

From FR

  • Virginie Couturaud · correspondingChristian Dior (France)
  • Marie Le FurChristian Dior (France)
  • Michele Pelletier
  • Frederic Granotier

Abstract

Background

Photobiomodulation is a process by which the absorption of red light energy produces a series of physiological effects at the cellular level such as the enhancement of mitochondrial Adenosine Triphosphate (ATP) production, cell signaling and growth factor synthesis, and the reduction of oxidative stress. Light emitting diodes (LEDs) photobiomodulation is an increasingly popular therapy for treating skin problems, especially for reversing the signs of skin aging.

Objective

The objective of this study is to demonstrate the effectiveness of a photobiomodulation treatment using red LEDs on the facial skin at a rate of two sessions per week for 3 months. The LED mask used is the Skin Light Dior x Lucibel mask diffusing a cold red light with a wavelength of 630 ± 10 nm and a power of 15.6 J/cm2 for a duration of 12 min.

Method

In order to demonstrate the effectiveness of the mask in reversing the signs of skin aging, a clinical study was conducted on 20 healthy Caucasian women: the antiwrinkle effect by measuring the depth of the crow's feet wrinkle, the relaxation of the oval of the face by clinical scoring, the firmness and elasticity of the skin by cutometric measurement, the density of the dermis by ultrasound analysis, the smoothness of the skin by measuring the roughness at the cheek, the homogeneity of the complexion by chromametric measurement, the diameter of the pores by macrophotographs and finally the sebo-regulating effect by measurement of the rate of sebum and quantification of the number of pores containing porphyrin in the subjects presenting a mixed to oily skin. The satisfaction of the volunteers was also evaluated at the end of the study via a self-questionnaire.

Results

The efficacy results measured after 1, 2, and 3 months of use are progressive and confirm the interest of LED photobiomodulation to reverse the visible signs of skin aging. All the volunteers observed an overall improvement in skin quality.

Conclusion

All the results observed confirm the interest of using photobiomodulation to reverse the visible signs of aging. These results last for up to 1 month after stopping the use of the mask, which is a sign of lasting structural and functional rejuvenation of the skin.

Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY-NC-ND).

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