Axial length shortening in myopic children with Stickler syndrome after repeated low-level red-light therapy
Tang XH, Yu MT, Hu Y, He MG, Yang X
International journal of ophthalmology · 9 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Case report (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2023-09-22 · Int J Ophthalmol · vol. 16 · issue 10 · pp. 1712–1717
- Publisher
- Press of International Journal of Ophthalmology (IJO PRESS)
- Cited
- 13 citations · more than 90% of similar papers · 2.6× the field average
- Impact
- Top 10% most cited in its field
- References
- 126 works
- Access
- Open access (journal) · CC-BY-NC-ND
- Research areas
- Connective tissue disorders research · Craniofacial Disorders and Treatments · Dermatological and Skeletal Disorders
- Keywords
- Medicine, Ophthalmology, Fundus (uterus), Visual acuity, Intraocular pressure
4 authors
From CN, AU
- Xiang-Hua TangSun Yat-sen University
- Yin Chang HuSun Yat-sen University
- Mingguang HeSun Yat-sen University; The University of Melbourne; Centre for Eye Research Australia; Melbourne Clinic
- Xiao ke YangSun Yat-sen University; The University of Melbourne; Centre for Eye Research Australia; Melbourne Clinic
Abstract
Aim
To report the myopia-controlling effect of repeated low-level red-light (RLRL) therapy in patients with Stickler syndrome (STL), an inherited collagenic disease typically presenting with early onset myopia.
Methods
Three STL children, aged 3, 7, and 11y, received RLRL therapy throughout the follow-up period of 17, 3, and 6mo, respectively after exclusion of fundus anomalies. Data on best-corrected visual acuity (BCVA), intraocular pressure, cycloplegic subjective refraction, ocular biometrics, scanning laser ophthalmoscope, optical coherence tomography, genetic testing, systemic disease history, and family history were recorded.
Results
At the initiation of the RLRL therapy, the spherical equivalent (SE) of 6 eyes from 3 patients ranged from -3.75 to -20.38 D, axial length (AL) were from 23.88 to 30.68 mm, and BCVA were from 0.4 to 1.0 (decimal notation). Myopia progression of all six eyes slowed down after RLRL therapy. AL in five out of the six eyes shortened -0.07 to -0.63 mm. No side effects were observed.
Conclusion
Three cases of STL whose progression of myopic shift and AL elongation are successfully reduced and even reversed after RLRL therapy.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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