Case report2025

Changing perspectives: unveiling the risks of ashwagandha-induced hepatotoxicity

Casiano-Manzano S, Torres-Larrubia M, Masa-Caballero A, Jiménez-Colmenarez Z, Martín-Noguerol E, Fernández-Bermejo M, Solís-Muñoz P

Revista espanola de enfermedades digestivas · 2 citations

Review labels

Funding not disclosed

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Case report (indexed by PubMed)
Studied in
People
Main outcome
Clinical events such as disease or death

Who paid for it

Funding
Funding not disclosed

Publication

Published
2023-01-01 · Rev Esp Enferm Dig · vol. 117 · issue 5 · pp. 288–289
Publisher
Arán Ediciones
Cited
5 citations · more than 76% of similar papers · 1.0× the field average
References
5 works
Access
Paywalled
Research areas
Drug-Induced Hepatotoxicity and Protection · Complementary and Alternative Medicine Studies · Pesticide Exposure and Toxicity
Keywords
Medicine, Alternative medicine, Traditional medicine, Intensive care medicine, Medicinal herbs, Liver damage, Pathology, Internal medicine
MeSH
humans, withania, plant extracts, medicine, ayurvedic, middle aged, male, chemical and drug induced liver injury

7 authors

From ES

  • Sergio Casiano-ManzanoComplejo Hospitalario de Cáceres
  • Macarena Torres-LarrubiaComplejo Hospitalario de Cáceres
  • Alberto Masa-CaballeroComplejo Hospitalario de Cáceres
  • Zuliani Jiménez-ColmenarezComplejo Hospitalario de Cáceres
  • Elisa Martín-NoguerolComplejo Hospitalario de Cáceres
  • Miguel Fernández‐BermejoComplejo Hospitalario de Cáceres

Abstract

Ashwagandha, an herb popular in Ayurvedic medicine, is renowned for its health-enhancing properties. However, its association with liver damage in recent years has raised significant concerns, necessitating careful assessment and management. This case underscores the dangers of Ashwagandha, particularly for individuals with preexisting liver conditions, where it can lead to life-threatening acute-on-chronic liver failure. The lack of solid clinical evidence supporting Ashwagandha's health claims emphasizes the need for an evidence-based approach. Public education is essential to raise awareness of the risks associated with herbal supplements and prevent liver diseases.

Abstract via Europe PMC. Copyright remains with the authors or publisher.

Community trust

Loading…

How much do you trust this study's findings?

0 · not at all10 · completely

Comments

Sign in to rate, comment on or flag this study.Sign in

Something wrong here?

Flag this study if its information, labels or funding look wrong. An editor reviews every flag.

Sign in to rate, comment on or flag this study.Sign in

Educational information about published research. Not medical advice, and not a recommendation to start or stop anything.