The efficacy of magnesium supplementation for gestational diabetes: A meta-analysis of randomized controlled trials
Luo L, Zhang Y, Wang H, Chen D, Li L
European journal of obstetrics, gynecology, and reproductive biology · 4 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Meta-analysis (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2023-12-12 · Eur J Obstet Gynecol Reprod Biol · vol. 293 · pp. 84–90
- Publisher
- Elsevier BV
- Cited
- 5 citations · more than 42% of similar papers · 0.3× the field average
- References
- 33 works
- Access
- Paywalled
- Research areas
- Magnesium in Health and Disease · Preterm Birth and Chorioamnionitis · Gestational Diabetes Research and Management
- Keywords
- Medicine, Gestational diabetes, Randomized controlled trial, Glycemic, Meta-analysis, Internal medicine, Cochrane Library, Gestational age, Diabetes mellitus, Insulin, Gestation, Gastroenterology, Pregnancy, Endocrinology
- MeSH
- humans, diabetes, gestational, insulin resistance, magnesium, pregnancy, dietary supplements, infant, newborn, female, randomized controlled trials as topic, insulins
9 authors
From CN
- Li-Wei Luo · correspondingFirst People's Hospital of Chongqing
- Li-Wei LuoFirst People's Hospital of Chongqing
- Y ZhangFirst People's Hospital of Chongqing
- Y Zhang · correspondingFirst People's Hospital of Chongqing
- Hao WangFirst People's Hospital of Chongqing
- HongMan Wang · correspondingFirst People's Hospital of Chongqing
Abstract
Background
The efficacy of magnesium supplementation is unclear for the treatment of gestational diabetes. This meta-analysis aimed to study the efficacy of magnesium supplementation for glycemic control and pregnant outcomes in women with gestational diabetes.
Methods
Several databases including PubMed, EMbase, Web of science, EBSCO, and Cochrane library databases have been systematically searched up to July 2023, and we included randomized controlled trials (RCTs) assessing the efficacy of magnesium supplementation for gestational diabetes. The meta-analysis was performed using the random-effect model or fixed-effect model based on the heterogeneity.
Results
Five RCTs and 266 patients were included in the meta-analysis. Overall, compared with control intervention for gestational diabetes, magnesium supplementation was able to significantly decrease FPG (MD = -7.33 mg/dL; 95 % CI = -7.64 to -7.02 mg/dL; P 2; 95 % CI = -0.06 to 0.04 kg/m2; P = 0.63).
Conclusions
Magnesium supplementation may be effective for the treatment of gestational diabetes without taking insulin treatment.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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