Funded in part by Egg Nutrition Center
Eggs and a Fiber-Rich Diet Are Beneficially Associated with Lipid Levels in Framingham Offspring Study Adults
Zhou X, Mott MM, Yiannakou I, Bradlee ML, Singer MR, Moore LL
Current developments in nutrition · 4 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Cohort study (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Not stated
Who paid for it
- Funding
- Industry funded
- Government
- U.S. Department of Health and Human Services
- Government
- U.S. Department of Agriculture
- University or hospital
- Boston University
- Industry group
- Egg Nutrition Center
- Government
- National Heart, Lung, and Blood Institute
- Government
- National Heart Lung and Blood Institute
- Grants
- Boston University (N01-HC-25195); National Heart, Lung, and Blood Institute (N01‐HC25195); National Heart, Lung, and Blood Institute (HHSN268201500001I); Boston University (HHSN268201500001I); National Heart, Lung, and Blood Institute (75N92019D00031)
Based on 6 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2024-02-22 · Curr Dev Nutr · vol. 8 · issue 3 · p. 102062
- Publisher
- Elsevier BV
- Cited
- 7 citations · more than 89% of similar papers · 2.7× the field average
- References
- 60 works
- Access
- Open access (journal) · CC-BY-NC-ND
- Research areas
- Nutritional Studies and Diet · Fatty Acid Research and Health · Birth, Development, and Health
- Keywords
- Offspring, Cholesterol, Medicine, Hazard ratio, Framingham Risk Score, Internal medicine, National Cholesterol Education Program, Endocrinology, Framingham Heart Study, Lower risk, Cohort, Prospective cohort study, Dietary Cholesterol, Physiology, Biology, Disease, Obesity, Metabolic syndrome, Pregnancy, Confidence interval
6 authors
From US
- Xinyi ZhouBoston University
- Melanie M. MottBoston University; EBSCO Industries (United States)
- Ioanna YiannakouBoston University
- M. Loring BradleeBoston University
- Martha R. SingerBoston University
- Lynn L. Moore · correspondingBoston University
Abstract
Background
For many years, United States' dietary policy recommended limiting egg intake to no more than 3/wk in the belief that restricting dietary cholesterol would lower plasma cholesterol levels and thereby reduce the risk of cardiovascular disease. The evidence supporting these recommendations is controversial.
Objectives
To examine the impact of eggs, a major contributor to dietary cholesterol intake, on lipid levels and to determine whether these egg effects are modified by other healthy dietary factors in adults.
Methods
Males and females aged 30-64 y with available 3-d diet record data, without cardiovascular disease and not taking lipid- or glucose-lowering medications in the prospective Framingham Offspring cohort were included (n = 1852). Analysis of covariance models were used to compare mean follow-up lipid levels adjusting for age, sex, BMI, and dietary factors. Cox proportional hazard's models were used to estimate risk for elevated lipid levels.
Results
Consuming ≥5 eggs/wk was not adversely associated with lipid outcomes. Among men, consuming ≥5 (compared with 160 mg/dL) LDL cholesterol levels (hazard ratio: 0.61; 95% confidence interval: 0.44, 0.84; and HR: 0.70; 95% confidence interval: 0.49, 0.98, respectively).
Conclusions
Higher egg intakes were beneficially associated with serum lipids among healthy adults, particularly those who consumed more fish and dietary fiber.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY-NC-ND).
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