Global disease burden linked to diet high in red meat and colorectal cancer from 1990 to 2019 and its prediction up to 2030
Yang X, Wu D, Liu Y, He Z, Manyande A, Fu H, Xiang H
Frontiers in nutrition · 15 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Cross-sectional study (classified by our AI screen)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Not stated
Who paid for it
- Funding
- Independent funding
- Government
- Ministry of Health, British Columbia
- Government
- Ministry of Finance
- Unclassified
- Research and Development
- Government
- Ministry of Health
Based on 4 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2024-03-14 · Front Nutr · vol. 11 · p. 1366553
- Publisher
- Frontiers Media
- Cited
- 19 citations · more than 98% of similar papers · 7.3× the field average
- Impact
- Top 10% most cited in its field
- References
- 60 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Nutritional Studies and Diet · Colorectal Cancer Screening and Detection · Agriculture Sustainability and Environmental Impact
- Keywords
- Medicine, Red meat, Colorectal cancer, Burden of disease, Demography, Disease burden, Index (typography), Environmental health, Mortality rate, Inequality, Disease, Gerontology, Cancer, Surgery, Internal medicine
7 authors
From CN, GB
- Xuesong YangTongji Hospital; Huazhong University of Science and Technology
- Duozhi WuHainan General Hospital
- Y J LiuTongji Hospital; Huazhong University of Science and Technology
- Zhigang HeTongji Hospital; Huazhong University of Science and Technology
- Anne ManyandeUniversity of West London
- Hongjun Fu · correspondingXiangyang Hospital of Traditional Chinese Medicine
Abstract
Background
Numerous studies have already identified an association between excessive consumption of red meat and colorectal cancer (CRC). However, there has been a lack of detailed understanding regarding the disease burden linked to diet high in red meat and CRC.
Objective
We aim to offer evidence-based guidance for developing effective strategies that can mitigate the elevated CRC burden in certain countries.
Methods
We used the data from the Global Burden of Disease (GBD) Study 2019 to evaluate global, regional, and national mortality rates and disability-adjusted Life years (DALYs) related to diet high in red meat. We also considered factors such as sex, age, the socio-demographic index (SDI), and evaluated the cross-national inequalities. Furthermore, we utilized DALYs data from 204 countries and regions to measure cross-country inequalities of CRC by calculating the slope index of inequality and concentration index as standard indicators of absolute and relative inequalities.
Discussion
The results show that globally, the age-standardized mortality rate (ASMR) and age-standardized disability adjusted life year rate (ASDR) related to CRC due to diet high in red meat have decreased, with estimated annual percent change (EAPCs) of -0.32% (95% CI -0.37 to -0.28) and-0.18% (95% CI -0.25 to -0.11). Notably, the burden was higher among males and the elderly. The slope index of inequality rose from 22.0 (95% CI 18.1 to 25.9) in 1990 to 32.9 (95% CI 28.3 to 37.5) in 2019 and the concentration index fell from 59.5 (95% CI 46.4 to 72.6) in 1990 to 48.9 (95% CI 34.6 to 63.1) in 2019. Also, according to our projections, global ASDR and ASMR might tend to increase up to 2030.
Conclusion
ASMR and ASDR for CRC associated with high red meat diets declined globally from 1990 to 2019, but the absolute number of cases is still rising, with men and the elderly being more affected. CRC associated with diets high in red meat exhibits significant income inequality, placing a disproportionate burden on wealthier countries. Moreover, according to our projections, ASMR and ASDR are likely to increase globally by 2030. In order to address this intractable disease problem, understanding changes in global and regional epidemiologic trends is critical for policy makers and others.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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