Painless Thyroiditis by Withania somnifera (Ashwagandha)
Hayashi M, Hamada H, Azuma SI, Hayashi K
Cureus · 10 citations
How it was studied
- Design
- Case report (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
Based on full-text disclosure statement.
Publication
- Published
- 2024-03-01 · Cureus · vol. 16 · issue 3 · p. e55352
- Publisher
- Cureus, Inc.
- Cited
- 10 citations · more than 95% of similar papers · 5.1× the field average
- Impact
- Top 10% most cited in its field
- References
- 17 works
- Access
- Open access (free to publish) · CC-BY
- Research areas
- Phytochemicals and Medicinal Plants
- Keywords
- Withania somnifera, Medicine, Thyroid, Thyroiditis, Subacute thyroiditis, Pediatrics, Traditional medicine, Internal medicine, Physiology, Pathology, Alternative medicine
4 authors
From JP
- Maho HayashiUniversity of Fukui Hospital; Fukui General Hospital
- Hina HamadaUniversity of Fukui Hospital; Fukui General Hospital
- Shin-Ichiro AzumaUniversity of Fukui Hospital; Fukui General Hospital
- Kôji Hayashi · correspondingUniversity of Fukui Hospital; Fukui General Hospital
Abstract
The Withania somnifera, also called Ashwagandha, is available everywhere in the world. We present a rare case of thyrotoxicosis following Ashwagandha administration, specifically painless thyroiditis (PT) in this report. The patient was a 47-year-old previously healthy Japanese man, who started taking Ashwagandha two months before his first visit to our hospital. He visited our hospital for typical thyrotoxicosis symptoms like a sense of fatigue, fever at night, and weight loss followed by diarrhea and headache. Blood tests disclosed thyrotoxicosis. Thyroid ultrasonography showed internal echo heterogeneity and no increase in blood flow. Thyroid scintigraphy revealed a deficiency in thyroid uptake. Based on these findings, he was diagnosed as PT. After stopping the administration of Ashwagandha, both his symptoms and serum thyroid markers were improved. This report may spark important debate about whether ashwagandha is safe among healthy people, especially in thyroid toxicity.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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