Olive oil intake and cardiovascular disease, cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective cohort studies
Ke Y, Fan H, Zhao Y, Fu X, Wang M, Gao Y, Chen Y, Huo W, Zhang W, Wang L, Wu Y, Li X, Zhang D, Hu F, Zhang M, Sun L, Lu J, Hu D
Food & function · 10 citations
How it was studied
- Design
- Meta-analysis (indexed by PubMed)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Not stated
Who paid for it
- Funding
- Independent funding
- Government
- National Natural Science Foundation of China
- Nonprofit
- Postdoctoral Research Foundation of China
- Government
- Science and Technology Planning Project of Shenzhen Municipality
- Government
- Basic and Applied Basic Research Foundation of Guangdong Province
- Grants
- Basic and Applied Basic Research Foundation of Guangdong Province (2022A1515010503); Science and Technology Planning Project of Shenzhen Municipality (JCYJ20210324093612032); National Natural Science Foundation of China (82273707); National Natural Science Foundation of China (82103940); Basic and Applied Basic Research Foundation of Guangdong Province (2021A1515012503); Postdoctoral Research Foundation of China (2021M692903); Science and Technology Planning Project of Shenzhen Municipality (JCYJ20220818095818040); National Natural Science Foundation of China (82304228); National Natural Science Foundation of China (81973152); National Natural Science Foundation of China (82073646)
Based on 4 listed funder(s).
Publication
- Published
- 2024-01-01 · Food Funct · vol. 15 · issue 9 · pp. 4668–4681
- Publisher
- Royal Society of Chemistry
- Cited
- 16 citations · more than 86% of similar papers · 2.0× the field average
- References
- 56 works
- Access
- Paywalled
- Research areas
- Nutritional Studies and Diet · Edible Oils Quality and Analysis · Antioxidant Activity and Oxidative Stress
- Keywords
- Medicine, Relative risk, Meta-analysis, Incidence (geometry), Cohort study, Stroke (engine), Internal medicine, Confidence interval, Cancer, Cause of death, Disease, Mortality rate
- MeSH
- humans, neoplasms, cardiovascular diseases, incidence, prospective studies, adult, middle aged, female, male, olive oil
18 authors
From CN
- Yamin KeZhengzhou University
- Haohao FanZhengzhou University
- Yang ZhaoZhengzhou University
- Xueru FuZhengzhou University
- Mengmeng WangZhengzhou University
- Yajuan GaoZhengzhou University
Abstract
Background: Currently, the reported links between olive oil intake and cardiovascular disease (CVD), cancer morbidity and mortality, and all-cause mortality are inconsistent. The aim of this meta-analysis is to study the reported correlations of olive oil intake with CVD, coronary heart disease (CHD), stroke and cancer incidence and mortality, and all-cause mortality. Methods: PubMed, Embase, and Web of Science were searched until March 7, 2024. Pooled relative risks (RRs) and 95% confidence intervals (CIs) were estimated by the random-effects model. Nonlinear dose-response relationships were modeled with restricted cubic splines. This study has been registered at PROSPERO (CRD42023419001). Results: Overall, 30 articles covering 2 710 351 participants were identified. Higher olive oil intake was linked with a reduced risk of CVD incidence (RR: 0.85; 95% CI: 0.77, 0.93), CHD incidence (RR: 0.85; 95% CI: 0.72, 0.99), CVD mortality (RR: 0.77; 95% CI: 0.67, 0.88), and all-cause mortality (RR: 0.85; 95% CI: 0.81, 0.89). For a 10 g d-1 increment of olive oil intake, the risk of CVD incidence, stroke incidence, CVD mortality, and all-cause mortality decreased by 7%, 5%, 8%, and 8%, respectively. No association was found between olive oil intake and cancer incidence and mortality. Nonlinear relationships between olive oil intake and CVD and all-cause mortality were observed, with a reduced risk from intakes ranging from 0 to 18 g d-1 and 0 to 22 g d-1, respectively. Conclusion: Our study found that high olive oil intake was related to a lower risk of CVD and CHD incidence and CVD mortality and all-cause mortality.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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