Meta-analysis2024Open access

Water Intake and Adiposity Outcomes among Overweight and Obese Individuals: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Chen QY, Khil J, Keum N

Nutrients · 4 citations

How it was studied

Design
Meta-analysis (indexed by PubMed)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Independent funding
Government
National Research Foundation
Government
National Research Foundation of Korea
Grants
National Research Foundation of Korea (BK21PLUS)

Based on 2 listed funder(s) and full-text disclosure statement.

Publication

Published
2024-03-27 · Nutrients · vol. 16 · issue 7 · p. 963
Publisher
Multidisciplinary Digital Publishing Institute
Cited
10 citations · more than 76% of similar papers · 1.3× the field average
References
55 works
Access
Open access (journal) · CC-BY
Research areas
Obesity, Physical Activity, Diet · Nutritional Studies and Diet · Diet, Metabolism, and Disease
Keywords
Medicine, Overweight, Meta-analysis, Randomized controlled trial, Waist, Body mass index, Confidence interval, Obesity, Weight management, Weight loss, Systematic review, Internal medicine, MEDLINE
MeSH
humans, obesity, body mass index, drinking, beverages, adult, female, male, adiposity, overweight, randomized controlled trials as topic, waist circumference

3 authors

From KR, US

  • Qiao-Yi ChenDongguk University
  • Jaewon KhilDongguk University
  • NaNa Keum · correspondingHarvard University; Dongguk University

Abstract

Background

Water consumption is believed to be a key factor in weight management strategies, yet the existing literature on the subject yields inconsistent findings. To systematically assess the scientific evidence regarding the effect of water intake on adiposity, we conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) among overweight and obese populations.

Methods

PubMed and Embase were searched for relevant articles published up to December 2023. The summary weighted mean difference (WMD) and 95% confidence interval (CI) were estimated using the DerSimonian-Laird random-effects model.

Results

In this meta-analysis of eight RCTs, interventions to promote water intake or to substitute water for other beverages as compared to the control group resulted in a summary WMD of -0.33 kg (95% CI = -1.75-1.08, I2 = 78%) for body weight, -0.23 kg/m2 (95% CI = -0.55-0.09, I2 = 0%) for body mass index (BMI), and 0.05 cm (95% CI = -1.20-1.30, I2 = 40%) for waist circumference (WC). Among RCTs substituting water for artificially sweetened beverages, summary WMD was 1.82 kg (95% CI = 0.97-2.67, I2 = 0%) for body weight and 1.23 cm (95% CI = -0.03-2.48, I2 = 0%) for WC. Conversely, among RCTs substituting water for sugar-sweetened beverages, summary WMD was -0.81 kg (95% CI = -1.66-0.03, I2 = 2%) for body weight and -0.96 cm (95% CI = -2.06-0.13, I2 = 0%) for WC.

Conclusions

In conclusion, water intake may not significantly impact adiposity among overweight and obese individuals. However, replacing sugar-sweetened beverages with water might offer a modest benefit in inducing weight loss.

Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).

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