Efficacy of repeated low-level red-light therapy in the prevention and control of myopia in children
Zhang H, Cui M, Jie Y, Chen T, Kang M, Bai W, Wang B, Wang Y
Photodiagnosis and photodynamic therapy · 14 citations
How it was studied
- Design
- Controlled clinical trial (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
- Government
- Beijing Municipal Health Commission
- University or hospital
- Capital Health Research and Development of Special Fund
Based on 2 listed funder(s).
Publication
- Published
- 2024-05-11 · Photodiagnosis Photodyn Ther · vol. 47 · p. 104216
- Publisher
- Elsevier BV
- Cited
- 16 citations · more than 95% of similar papers · 4.2× the field average
- Impact
- Top 10% most cited in its field
- References
- 34 works
- Access
- Open access (journal) · CC-BY-NC-ND
- Research areas
- Ophthalmology and Visual Impairment Studies · Corneal surgery and disorders · Retinopathy of Prematurity Studies
- Keywords
- Dioptre, Medicine, Ophthalmology, Significant difference, Red light, Light therapy, Visual acuity, Internal medicine, Circadian rhythm
- MeSH
- humans, myopia, refraction, ocular, adolescent, child, child, preschool, female, male, low-level light therapy
8 authors
From CN
- Hao Zhang · correspondingCapital Institute of Pediatrics; Children's Hospital of Capital Institute of Pediatrics
- Mingming CuiCapital Institute of Pediatrics
- Ying JieBeijing Tongren Hospital; Capital Medical University
- Ting ChenChildren's Hospital of Capital Institute of Pediatrics
- Meixia KangChildren's Hospital of Capital Institute of Pediatrics
- Wanbing BaiChildren's Hospital of Capital Institute of Pediatrics
Abstract
Objective
In this study, we aimed to determine how different factors influence the effectiveness of repeated low-level red-light (RLRL) therapy in preventing and treating myopia in children.
Methods
Between June 2022 and April 2023, 336 children who visited our hospital due to myopia or significant decreases in hyperopia reserve were enrolled. The children were treated twice daily for three minutes with a head-mounted low-level red-light (single wavelength of 650 nm) therapeutic device. Each of the two treatment sessions was separated by at least four hours. The axial lengths and diopters of the children's eyes were compared before and three months after treatment, and the effects of gender, age, and baseline diopter on the efficacy of RLRL therapy were analyzed.
Results
Following three months of treatment, the average axial length of the eyes decreased by 0.031 mm. The condition was better for the boys than for girls, but the difference was not statistically significant. As age increased (F = 8.112, P = 0.000) or as the absolute value of baseline myopia degree increased (F = 10.51, P = 0.000), axial lengths of the eyes tended to decrease. The spherical equivalent refraction (SER) of children decreased by an average of 0.012 ± 0.355D. The condition was better for the boys than for girls, but the difference was not statistically significant. SER increased in the direction of hyperopic drift as age increased (F = 2.48, P = 0.031), or as the absolute value of baseline myopia degrees increased (F = 6.835, P = 0.000). There were no obvious side effects following the treatment.
Conclusion
This study showed that RLRL therapy is a potential efficient, easily operable, and practically feasible method for the prevention and control of myopia.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY-NC-ND).
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