Mediterranean diet enriched with olive oil shows no consistent benefits on cardiometabolic and anthropometric parameters: a systematic review with meta-analysis of randomized controlled trials
Keshani M, Sadeghi N, Tehrani SD, Ahmadi AR, Sharma M
European journal of nutrition · 7 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Meta-analysis (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Not stated
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2024-08-17 · Eur J Nutr · vol. 63 · issue 8 · pp. 2835–2857
- Publisher
- Springer Science+Business Media
- Cited
- 10 citations · more than 76% of similar papers · 1.3× the field average
- References
- 73 works
- Access
- Paywalled
- Research areas
- Nutritional Studies and Diet · Edible Oils Quality and Analysis · Fatty Acid Research and Health
- Keywords
- Medicine, Mediterranean diet, Meta-analysis, Cochrane Library, Olive oil, Randomized controlled trial, CINAHL, MEDLINE, Environmental health, Internal medicine, Food science, Biology
- MeSH
- humans, cardiovascular diseases, lipids, triglycerides, anthropometry, diet, mediterranean, blood pressure, randomized controlled trials as topic, olive oil
5 authors
From IR, US
- Mahdi Keshani · correspondingIsfahan University of Medical Sciences
- Narges SadeghiAhvaz Jundishapur University of Medical Sciences
- Sahar Dadkhah TehraniIsfahan University of Medical Sciences
- Amirhossein Ramezani AhmadiIsfahan University of Medical Sciences
- Manoj SharmaUniversity of Nevada, Las Vegas
Abstract
Purpose
Cardiovascular disease (CVD) is the primary cause of death worldwide but there is a variation in its burden across some nations that seems to be related to dietary habits. Mediterranean populations have lower rates of morbidity and mortality from CVD. Thus, this systematic review and meta-analysis aimed to assess the impacts of the Mediterranean diet (MedDiet) enriched with olive oil on blood lipids, glycemic indices, blood pressure, and anthropometric indices.
Methods
A comprehensive search of the Web of Science, PubMed (MEDLINE), Scopus, Cochrane Library, Google Scholar, Embase, and CINAHL databases until March 2024 was conducted to identify clinical trials studying the effects of MedDiet enriched with olive oil on the aforementioned parameters.
Results
In total, 3303 records were retrieved. A total of 18 clinical trials met the inclusion criteria after records were screened for eligibility. According to the pooled analysis from the random-effects model, the MedDiet enriched with olive oil significantly reduced triglycerides (TG) compared with the control group (WMD = -2.40 mg/dl; 95%CI, -4.533 to -0.262; P = 0.027). Strong heterogeneity was observed. Sensitivity analysis did not change our results and no significant effect of any trial on the overall effect sizes of all variables were found. There was a concern about the reporting bias for some studies which reported some main outcomes.
Conclusion
MedDiet enriched with olive oil showed no consistent effects on any of the reported markers of cardiovascular health except on TG.
Systematic review registration
CRD42023424641.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
Community trust
Loading…
How much do you trust this study's findings?
Comments
Sign in to rate, comment on or flag this study.Sign inSomething wrong here?
Flag this study if its information, labels or funding look wrong. An editor reviews every flag.
Sign in to rate, comment on or flag this study.Sign inEducational information about published research. Not medical advice, and not a recommendation to start or stop anything.