Study2024Open access

Hypermagnesemia caused by fecal-mass obstruction in stenotic rectal cancer following preoperative administration of magnesium citrate

Sato Y, Hashiba E, Yamazaki Y, Kato K, Kinoshita H, Noguchi S, Kudo T, Hirota K

JA clinical reports · 0 citations

How it was studied

Design
Case report (classified by our AI screen)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Independent funding
Government
Japan Society for the Promotion of Science
Grants
Japan Society for the Promotion of Science (24K19449)

Based on 1 listed funder(s) and full-text disclosure statement.

Publication

Published
2024-12-20 · JA Clin Rep · vol. 10 · issue 1 · p. 77
Publisher
Springer Nature
Cited
3 citations · more than 67% of similar papers · 0.6× the field average
References
9 works
Access
Open access (journal) · CC-BY
Research areas
Magnesium in Health and Disease · Esophageal and GI Pathology · Enhanced Recovery After Surgery
Keywords
Medicine, Hypermagnesemia, Anesthesia, Cathartic, Fecal impaction, Surgery, Magnesium, Hypomagnesemia, Constipation

8 authors

From JP

  • Yuri A. Sato · correspondingAomori Prefectural Central Hospital
  • Eiji HashibaHirosaki University
  • Yuuma YamazakiKensei Hospital
  • Koudai KatoAomori Prefectural Central Hospital
  • Hirotaka KinoshitaHirosaki University
  • Satoko NoguchiHirosaki University

Abstract

Background

Hypermagnesemia is a rare complication, leading to fatal cardiovascular and respiratory conditions. We present severe hypermagnesemia developed in a patient with a rectal stenosis after pretreatment with oral magnesium citrate for rectosigmoid surgery.

Case presentation

A 78-year-old woman demonstrated consciousness disturbance, muscle weakness, and respiratory depression requiring tracheal intubation after preparation with oral magnesium for rectosigmoid surgery. Endoscopic examination showed a rectal obstruction due to fecal impaction. General condition improved after emergency Hartmann's surgery. Blood test revealed a remarkable increase of serum magnesium level to 17.5 mg/dL when the general condition deteriorated, which would have been responsible for her symptoms. She was discharged from the ICU after extubation on the third postoperative day with a normal magnesium level.

Conclusions

Pretreatment with large doses of oral magnesium-containing bowel cleanser may cause severe hypermagnesemia in patients with colorectal stenosis.

Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).

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