Egg Consumption and Mortality: A Prospective Cohort Study of Australian Community-Dwelling Older Adults
Wild H, Gasevic D, Woods RL, Ryan J, Wolfe R, Chen Y, Govindaraju T, McNeil JJ, McCaffrey T, Beilin LJ, Ilic D, Owen AJ
Nutrients · 1 citation
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Cohort study (indexed by PubMed)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Food frequency questionnaire
Who paid for it
- Funding
- Independent funding
- Government
- National Health and Medical Research Council
- Government
- National Institute on Aging
- Government
- NIA NIH HHS
- Grants
- National Institute on Aging (U01 AG029824); National Institute on Aging (U19 AG062682)
Based on 3 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2025-01-17 · Nutrients · vol. 17 · issue 2 · p. 323
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 2 citations · more than 82% of similar papers · 1.8× the field average
- References
- 50 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Nutritional Studies and Diet · Nutrition and Health in Aging · Antioxidant Activity and Oxidative Stress
- Keywords
- Prospective cohort study, Gerontology, Medicine, Cohort study, Cohort, Environmental health, Demography, Internal medicine
- MeSH
- humans, neoplasms, cardiovascular diseases, diet, mortality, cause of death, proportional hazards models, risk factors, longitudinal studies, prospective studies, eggs, aged, aged, 80 and over, australia, female, male, independent living
12 authors
From AU, GB
- Holly WildMonash University
- Danijela GaševićMonash University; University of Edinburgh
- Robyn L. WoodsMonash University
- Joanne L. RyanMonash University
- Rory WolfeMonash University
- Yuquan ChenMonash University
Abstract
Background/objectives
Egg consumption in adults has been linked with a modestly increased risk of all-cause and CVD mortality. However, evidence on adults aged 65 y+ is limited. The objective of this study was to investigate the association between egg intake and mortality in community-dwelling older adults.
Methods
In this prospective cohort study, 8756 adults aged 70+ years, participants in the ASPirin in Reducing Events in the Elderly (ASPREE) Longitudinal Study of Older Persons, self-reported the frequency of their total egg intake: never/infrequently (rarely/never, 1-2 times/month), weekly (1-6 times/week), and daily (daily/several times per day). All-cause and cause-specific (cardiovascular disease [CVD] and cancer) mortality was established from at least two sources: medical records, death notices, next of kin, or death registry linkage. The association between egg intake and mortality was assessed using Cox proportional hazards regression analysis, adjusted for socio-demographic, health-related, and clinical factors and overall dietary quality.
Results
Over the median 5.9-year follow-up period, a total of 1034 all-cause deaths (11.8%) were documented. A 29% lower risk of CVD mortality (HR (95% CI): 0.71 [0.54-0.92]) and a 17% (HR (95% CI): 0.83 [0.71-0.96]) lower risk of all-cause mortality were observed among those who consumed eggs weekly, compared to those who consumed eggs never/infrequently; no statistically significant association was observed for weekly consumption and cancer mortality. In contrast, compared to those that never or infrequently consumed eggs, daily consumption had slightly higher odds of mortality, though these results did not reach statistical significance.
Conclusions
The consumption of eggs 1-6 times per week was associated with a lower risk of all-cause mortality and CVD mortality in community-dwelling adults aged 70 years and over. These findings may be important to inform the development of evidence-based guidelines for egg consumption.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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