Cohort study2025Open access

Ultraprocessed Food Consumption and Obesity Development in Canadian Children

Chen ZH, Mousavi S, Mandhane PJ, Simons E, Turvey SE, Moraes TJ, Subbarao P, Miliku K

JAMA network open · 21 citations

Review labels

Food frequency questionnaireNo stated lifestyle adjustment

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Cohort study (indexed by PubMed)
Studied in
People
Main outcome
Health markers and function
Intake measured by
Food frequency questionnaire

Who paid for it

Funding
Independent funding
Government
Genome Canada
University or hospital
McMaster University
University or hospital
BC Children's Hospital
University or hospital
University of Alberta
University or hospital
University of Toronto
University or hospital
Hospital for Sick Children
Government
Canadian Institutes of Health Research
University or hospital
Faculty of Medicine and Health, University of Sydney

Based on 8 listed funder(s).

Publication

Published
2025-01-31 · JAMA Netw Open · vol. 8 · issue 1 · p. e2457341
Publisher
American Medical Association
Cited
27 citations · more than 100% of similar papers · 24.0× the field average
Impact
Top 10% most cited in its field
References
41 works
Access
Open access (journal) · CC-BY
Research areas
Consumer Attitudes and Food Labeling · Global Public Health Policies and Epidemiology · Nutrition, Genetics, and Disease
Keywords
Medicine, Anthropometry, Body mass index, Obesity, Waist, Demography, Population, Cohort, Childhood obesity, Prospective cohort study, Environmental health, Pediatrics, Overweight, Internal medicine
MeSH
humans, body mass index, diet, prospective studies, food handling, child, preschool, canada, female, male, adiposity, fast foods, pediatric obesity

8 authors

From CA, MY

  • Zheng Hao ChenUniversity of Toronto
  • Sara MousaviUniversity of Toronto
  • Piush J. MandhaneUniversity of Alberta; UCSI University
  • Elinor SimonsUniversity of Manitoba
  • Stuart E. TurveyUniversity of British Columbia; BC Children's Hospital
  • Theo J. MoraesUniversity of Toronto; Hospital for Sick Children; SickKids Foundation

Abstract

Importance

Ultraprocessed foods (UPF), characterized as shelf-stable but nutritionally imbalanced foods, pose a public health crisis worldwide. In adults, UPF consumption is associated with increased obesity risk, but findings among children are inconsistent.

Objectives

To examine the associations among UPF intake, anthropometric adiposity indicators, and obesity status in Canadian children.

Design, setting, and participants

In the CHILD Cohort Study, one of the largest prospective, multicenter, population-based pregnancy cohorts in Canada, diet was assessed during the 3-year visit (September 2011 to June 2016), and anthropometric measurements were assessed at the 5-year visit (December 2013 to April 2018). Data analysis was performed between July 1, 2023, and June 30, 2024.

Exposure

Diet intake was assessed using a semiquantitative food frequency questionnaire at 3 years of age. UPFs were identified using the NOVA classification system.

Main outcomes and measures

Anthropometric adiposity indicators were measured at 5 years of age and used to calculate age- and sex-standardized z scores for body mass index (BMI), waist to height ratio, and subscapular and triceps skinfold thicknesses, and obesity, which was defined using BMI z score cutoffs. Multivariable-adjusted regression analyses were used to examine the associations of UPF with adiposity and obesity development, accounting for parental, birth, and early-childhood factors.

Results

Among 2217 participants included in this study, median age at the outcome assessment was 5.0 (IQR, 5.0-5.1) years, and 1175 (53.0%) were males. At 3 years of age, UPF contributed 45.0% of total daily energy intake. UPF energy contribution was higher in males vs females (46.0% vs 43.9%; P < .001). Among all participants, higher UPF intake at 3 years of age was associated with higher anthropometric adiposity indicators at 5 years of age, primarily driven by males. In males, every 10% UPF energy increase was associated with higher adiposity indicator z scores for BMI (β, 0.08; 95% CI, 0.03-0.14), waist to height ratio (β, 0.07; 95% CI, 0.01-0.12), and subscapular (β, 0.12; 95% CI, 0.06-0.18) and triceps (β, 0.09; 95% CI, 0.03-0.15) skinfold thickness and higher odds of living with overweight or obesity (odds ratio, 1.19; 95% CI, 1.03-1.36). No significant associations were observed among females.

Conclusions and relevance

In this cohort study of Canadian children, high UPF consumption during early childhood was associated with obesity development, primarily in males. These findings can inform targeted public health initiatives for early childhood centers and caregiver education programs to reduce UPF intake and prevent obesity.

Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).

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