Study2025

Effects of repeated low-level red-light therapy on myopia control in children with intermittent exotropia

Qian Y, Li X, Zhu Y, Qi X, Yu G, Zhang F, Guo L, Ku W, Qian X

Photodiagnosis and photodynamic therapy · 5 citations

How it was studied

Design
Controlled clinical trial (classified by our AI screen)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Independent funding
University or hospital
Tianjin Medical University Eye Hospital

Based on 1 listed funder(s).

Publication

Published
2025-02-19 · Photodiagnosis Photodyn Ther · vol. 52 · p. 104526
Publisher
Elsevier BV
Cited
3 citations · more than 84% of similar papers · 1.9× the field average
References
41 works
Access
Open access (journal) · CC-BY
Research areas
Ophthalmology and Eye Disorders · Ophthalmology and Visual Impairment Studies · Corneal surgery and disorders
Keywords
Intermittent exotropia, Medicine, Ophthalmology, Exotropia, Strabismus
MeSH
humans, exotropia, myopia, refraction, ocular, treatment outcome, retrospective studies, child, child, preschool, female, male, low-level light therapy

9 authors

From CN

  • Yichao Qian · correspondingTianjin Medical University Eye Hospital; Tianjin Medical University
  • Xiangyun LiZoucheng People's Hospital
  • Yawen ZhuTianjin Medical University Eye Hospital; Tianjin Medical University
  • Xiaoli QiTianjin Medical University Eye Hospital; Tianjin Medical University
  • Gang Yu
  • Feng ZhangBeijing Haidian Hospital

Abstract

Background

The optimal myopia control measures for children with intermittent exotropia (IXT) have yet to be determined. This study evaluates the impact of Repeated low-level red-light therapy (RLRL) on myopia control in this population.

Methods

This retrospective study included 94 participants divided into three groups: Myopic children without strabismus receiving RLRL treatment (RLRL Group).Children with IXT and myopia undergoing RLRL treatment (IXT with RLRL Group).ChJournal Titleildren with IXT and myopia not receiving any myopia control interventions(Control Group).Axial length (AL) and spherical equivalent refraction (SER) were measured before and after the intervention. For patients with IXT, distance and near exodeviation angles and near stereopsis were also assessed.

Results

Post-RLRL treatment, the IXT with RLRL Group exhibited significantly less AL elongation compared to the Control Group at various time points (P0.05). Additionally, no significant differences in AL and SER control were observed between the IXT with RLRL Group and the RLRL Group (P>0.05), and treatment efficacy was similar between the two eyes.

Conclusions

RLRL is effective in controlling myopia progression in children with IXT without adversely affecting strabismus parameters. Its efficacy is comparable to that observed in children without strabismus, suggesting RLRL as a viable option for myopia management in this population.

Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).

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