Dose-response relationship of egg consumption with cognitive function in rural older adults: a large-scale population-based study
Ren T, Yuchi Y, Feng L, Wang X, Liao W, Tian Z, Zhang H, Tian Y, Li Y, Wang C
Frontiers in nutrition · 1 citation
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Cross-sectional study (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Food frequency questionnaire
Who paid for it
- Funding
- Independent funding
- Government
- Natural Science Foundation of Henan Province
Based on 1 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2025-05-20 · Front Nutr · vol. 12 · p. 1566659
- Publisher
- Frontiers Media
- Cited
- 1 citation · more than 73% of similar papers · 0.9× the field average
- References
- 35 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Nutritional Studies and Diet · Dementia and Cognitive Impairment Research · Fatty Acid Research and Health
- Keywords
- Scale (ratio), Cognition, Consumption (sociology), Population, Gerontology, Function (biology), Psychology, Medicine, Demography, Environmental health, Geography, Biology, Cartography, Psychiatry
10 authors
From CN
- Tingyun RenZhengzhou University
- Yinghao YuchiZhengzhou University
- Lange FengZhengzhou University
- Xinlai WangMudanjiang Medical University
- Wei LiaoZhengzhou University
- Zhenzhen TianZhengzhou University
Abstract
Background
Previous studies had accessed the effect of egg consumption on cognitive function, but the general population-based evidence is limited and inconclusive. In addition, the optimal intake of egg remains unclear. The study aimed to investigate the association of egg consumption with mild cognitive impairment (MCI) in rural adults and then explore the recommended intake of eggs.
Methods
This study included 14,550 participants from the second wave of the Henan Rural Cohort Study. Egg consumption was assessed using a validated food frequency questionnaire. Cognitive function was measured using the Mini-Mental State Examination (MMSE). MCI was defined as MMSE scores ≤ 17 for illiteracy, ≤ 20 for primary school education, or ≤ 24 for junior high school education or higher. Logistic regression analyzed the relationship between egg intake and MCI. Dose-response relationships were evaluated using restricted cubic spline (RCS) models.
Results
The adjusted odds ratio (OR) and 95% confidence interval (CI) of per SD increase of daily egg consumption for MCI was 0.925 (0.891, 0.960). A U-shape dose-response relationship between egg consumption and MCI was found (p OR (95%CI) per SD increase of egg consumption below and above the optimal intake (87.94 g/day) was 0.826 (0.774, 0.880) and 1.188 (1.056, 1.336), respectively. Sensitivity analyses showed similar results.
Conclusion
Egg consumption is associated with cognitive function among rural populations and eat egg 87.94 g/day could have best benefit, supporting its potential role in dietary strategies for cognitive health.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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