Efficacy of repeated low-level red-light therapy combined with defocus incorporated multiple segments spectacles for controlling childhood myopia
Luo CK, Lai CY, Tan JH, Zhao W, Tan QQ
Photodiagnosis and photodynamic therapy · 4 citations
How it was studied
- Design
- Controlled clinical trial (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
- University or hospital
- North Sichuan Medical College
Based on 1 listed funder(s).
Publication
- Published
- 2025-06-13 · Photodiagnosis Photodyn Ther · vol. 54 · p. 104681
- Publisher
- Elsevier BV
- Cited
- 5 citations · more than 92% of similar papers · 3.1× the field average
- Impact
- Top 10% most cited in its field
- References
- 34 works
- Access
- Open access (journal) · CC-BY-NC-ND
- Research areas
- Ophthalmology and Visual Impairment Studies · Corneal surgery and disorders · Retinopathy of Prematurity Studies
- Keywords
- Medicine, Optometry, Ophthalmology
- MeSH
- humans, myopia, refraction, ocular, treatment outcome, eyeglasses, adolescent, child, female, male, low-level light therapy
5 authors
From CN
- Chang-Kang LuoNorth Sichuan Medical University; Affiliated Hospital of North Sichuan Medical College
- Chun-Yan LaiNorth Sichuan Medical University; Affiliated Hospital of North Sichuan Medical College
- Jia-Hao Tan · correspondingNorth Sichuan Medical University; Affiliated Hospital of North Sichuan Medical College
- Wei ZhaoNorth Sichuan Medical University; Affiliated Hospital of North Sichuan Medical College
- Qing‐Qing Tan · correspondingNorth Sichuan Medical University
Abstract
Objective
To evaluate the differences in the efficacy of repeated low-level red-light (RLRL) therapy combined with either single-vision spectacles (SVS) or defocus incorporated multiple segments (DIMS) spectacles in slowing myopia progression in children.
Methods
A total of 129 myopic children aged 6-14 years were recruited between July 2023 and February 2024. Participants had at least one eye with spherical equivalent refraction (SER) <-0.50D and astigmatism ≤ 3.00D after cycloplegia. They were divided into four groups: SVS, DIMS, RLRL combined with SVS (RCS), and RLRL combined with DIMS (RCD). The RCS and RCD groups wore spectacles and received daily RLRL therapy sessions. The primary outcome was the change in axial length (AL) at 12 months.
Results
After 12 months, the mean changes of AL were: 0.26 mm (95 % CI, 0.17 to 0.35 mm) for SVS, 0.16 mm (95 % CI, 0.11 to 0.21 mm) for DIMS, -0.21 mm (95 % CI, -0.45 to 0.02 mm) for RCS, and -0.14 mm (95 % CI, -0.27 to -0.01 mm) for RCD. Significant differences were observed between groups (F = 15.18, P 0.05). No severe adverse events or safety concerns related to RLRL therapy were observed throughout the study.
Conclusion
RLRL therapy is a potentially effective and practical approach for myopia control, demonstrating comparable efficacy when combined with either SVS or DIMS spectacles.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY-NC-ND).
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