Effect of Magnesium Supplements on Improving Glucose Control, Blood Pressure and Lipid Profile in Patients With Type 2 Diabetes Mellitus: <i>A systematic review and meta-analysis</i>
Maqrashi NA, Busaidi SA, Al-Rasbi S, Alawi AMA, Al-Maqbali JS
Sultan Qaboos University medical journal · 3 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Meta-analysis (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2025-05-16 · Sultan Qaboos Univ Med J · vol. 25 · issue 1 · pp. 382–394
- Publisher
- Sultan Qaboos University
- Cited
- 9 citations · more than 90% of similar papers · 2.5× the field average
- Impact
- Top 10% most cited in its field
- References
- 5 works
- Access
- Open access (free to publish) · CC-BY
- Research areas
- Social and Behavioral Studies · Magnesium in Health and Disease · Apelin-related biomedical research
- Keywords
- Medicine, Diabetes mellitus, Lipid profile, Meta-analysis, Blood pressure, Type 2 Diabetes Mellitus, Internal medicine, Type 2 diabetes, Endocrinology
- MeSH
- humans, diabetes mellitus, type 2, magnesium, blood glucose, lipids, blood pressure, dietary supplements, aged, female, male, randomized controlled trials as topic, glycemic control, glycated hemoglobin
5 authors
From OM
- Nasiba Al-MaqrashiOman Medical College
- Salim Al BusaidiSultan Qaboos University Hospital
- Sara Al-RasbiSultan Qaboos University Hospital
- Abdullah Mohammed Al AlawiOman Medical College; Sultan Qaboos University Hospital
- Juhaina Salim Al-MaqbaliSultan Qaboos University Hospital
Abstract
This study evaluated the effects of magnesium (Mg) supplementation on glycaemic control in type 2 diabetes mellitus through a meta-analysis of 23 randomised controlled trials involving 1,345 participants. Mg supplementation significantly increased serum Mg levels (weighted mean difference [WMD] = 0.69, 95% CI: 0.32 to 1.06) and reduced fasting blood glucose levels (WMD = -0.58, 95% CI: -0.87 to -0.28). However, the impact on glycated haemoglobin was minimal (WMD = -0.16, 95% CI: -0.32 to 0.00). Subgroup analysis showed a greater reduction in glycated haemoglobin among participants aged ≥65 years and those receiving longer durations of supplementation. Additionally, Mg supplementation was linked to lower diastolic blood pressure and potential improvements in lipid profile. This review highlights the importance of considering patient characteristics, dosage and intervention duration in future research on Mg supplementation for glycaemic control in diabetes.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY-ND).
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