Effect of the Mediterranean diet supplemented with olive oil versus the Mediterranean diet supplemented with mixed nuts on blood pressure and serum lipid indexes among adults: a systematic review and meta-analysis of randomized controlled trials
Pourrajab B, Mirdar Harijani A, Asghari P, Shidfar F
Nutrition, metabolism, and cardiovascular diseases : NMCD · 1 citation
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Meta-analysis (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Not stated
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2025-06-18 · Nutr Metab Cardiovasc Dis · vol. 35 · issue 11 · p. 104166
- Publisher
- Elsevier BV
- Cited
- 2 citations · more than 53% of similar papers · 0.5× the field average
- References
- 68 works
- Access
- Paywalled
- Research areas
- Nuts composition and effects · Nutritional Studies and Diet · Edible Oils Quality and Analysis
- Keywords
- Mediterranean diet, Dyslipidemia, Meta-analysis, Blood pressure, Olive oil, Medicine, Lipid profile, Internal medicine, Blood lipids, Food science, Disease, Biology, Cholesterol
- MeSH
- humans, nuts, hypertension, lipids, treatment outcome, risk assessment, risk reduction behavior, diet, mediterranean, blood pressure, dietary supplements, adult, aged, middle aged, female, male, dyslipidemias, randomized controlled trials as topic, biomarkers, olive oil, diet, healthy
4 authors
From IR
- Behnaz PourrajabNational Nutrition and Food Technology Research Institute; Shahid Beheshti University of Medical Sciences
- Artemiss Mirdar HarijaniIran University of Medical Sciences
- Parastoo AsghariMashhad University of Medical Sciences
- Farzad Shidfar · correspondingIran University of Medical Sciences
Abstract
Background and aim
Hypertension and dyslipidemia are major risk factors for cardiovascular disease (CVD). This systematic review and meta-analysis compared the effects of two Mediterranean (MED) dietary patterns-one supplemented with olive oil and the other with mixed nuts-on blood pressure and lipid profile.
Methods and results
Relevant studies published until April 24, 2024, were thoroughly searched in online databases, including PubMed/Medline, Scopus, Clarivate Analytics' Web of Science, Cochrane Central Register of Controlled Trials, and Google Scholar. The analysis included 21 trials with 25 effect sizes, calculated as standardized mean differences with 95 % confidence intervals (CI). The findings indicated that the MED diet supplemented with olive oil has no significant effect on lipid indices and diastolic blood pressure (DBP) when contrasted with the MED diet supplemented with mixed nuts. However, the olive oil group had slightly higher systolic blood pressure levels than the mixed nuts group, with a significant p-value of <0.001.
Conclusions
Evidence indicates no significant difference in serum lipid profile and DBP between the MED diet supplemented with olive oil and that with mixed nuts in participants at risk of CVD. However, mixed nuts significantly reduce SBP compared to olive oil. More studies on diverse populations are needed.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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