Benefits of Krill Oil Supplementation During Alternate-Day Fasting in Adults With Overweight and Obesity: A Randomized Trial
Alblaji M, Gray SR, Almesbehi T, Morrison DJ, Malkova D
Obesity (Silver Spring, Md.) · 2 citations
How it was studied
- Design
- Randomized controlled trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
- University or hospital
- Qassim University
- Government
- Government of Saudi Arabia
Based on 2 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2025-07-16 · Obesity (Silver Spring) · vol. 33 · issue 9 · pp. 1694–1703
- Publisher
- Wiley
- Cited
- 3 citations · more than 84% of similar papers · 1.6× the field average
- References
- 52 works
- Access
- Open access (hybrid journal) · CC-BY
- Research areas
- Dietary Effects on Health · Muscle metabolism and nutrition · Fatty Acid Research and Health
- Keywords
- Medicine, Overweight, Placebo, Animal science, Krill, Obesity, Randomized controlled trial, Internal medicine, Endocrinology, Biology
- MeSH
- animals, humans, euphausiacea, obesity, weight loss, xanthophylls, docosahexaenoic acids, eicosapentaenoic acid, body mass index, hand strength, fasting, double-blind method, body composition, dietary supplements, adult, middle aged, female, male, overweight
5 authors
From SA, GB, LT
- Mansour AlblajiQassim University; University of Glasgow
- Stuart Robert GrayLithuanian Sports University; University of Glasgow
- Taibah AlmesbehiUniversity of Glasgow
- Douglas J. MorrisonScottish Universities Environmental Research Centre
- Dalia Malkova · correspondingUniversity of Glasgow
Abstract
Objective
To investigate the effect of krill oil (KO) supplementation during alternate-day fasting (ADF) on body composition and muscle function in healthy adults with overweight.
Methods
In a randomized trial, during the 8-week ADF, participants consumed four capsules per day containing krill oil (KO group) or vegetable oil (placebo group). Each capsule of KO contained 191 mg EPA, 94 mg DHA, 78 mg choline, and 100 mcg astaxanthin. Body mass, fat-free mass (FFM), and handgrip strength (HGS) were measured before and after the intervention. Data were analyzed using ANOVA.
Results
The study was completed by 41 (25 women and 16 men) participants (age: 39 ± 10 years, BMI: 31.1 ± 4.2 kg/m2). Body weight reduction was not different (p > 0.05) between groups (KO, -4.6 ± 1.4 kg; Placebo, -4.5 ± 1.9 kg). The KO group had no change (p > 0.05) in FFM (-0.2 ± 0.9 kg) or HGS (-0.2 ± 0.5 kg). The placebo group experienced a reduction (p < 0.05) in FFM (-1.2 ± 2.0 kg) and HGS (-0.9 ± 0.7 kg). Changes in FFM and HGS were different (p < 0.05) between groups.
Conclusions
KO supplementation during body weight loss attenuates the decline in FFM and muscle strength.
Trial registration
ClinicalTrials.gov Identifier (NCT06001632).
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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