Funded in part by The Beef Checkoff
Effect of unprocessed red meat on obesity and related factors: A systematic review and meta-analysis
Akheruzzaman M, Hefner M, Baller D, Clark S, Feizy Z, Thomas DM, Dhurandhar NV
Obesity (Silver Spring, Md.) · 5 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Meta-analysis (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Not stated
Who paid for it
- Funding
- Industry funded
- University or hospital
- Texas Tech University
- Government
- National Institutes of Health
- Industry group
- The Beef Checkoff
- Government
- NIH HHS
- Authors
- At least one author declares a financial tie to industry
- Grants
- National Institutes of Health (AOD22022001)
Based on 4 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2025-07-25 · Obesity (Silver Spring) · vol. 33 · issue 9 · pp. 1627–1636
- Publisher
- Wiley
- Cited
- 4 citations · more than 65% of similar papers · 0.8× the field average
- References
- 60 works
- Access
- Open access (hybrid journal) · CC-BY
- Research areas
- Agriculture Sustainability and Environmental Impact · Meat and Animal Product Quality · Nutritional Studies and Diet
- Keywords
- Meta-analysis, Red meat, Obesity, Food science, Medicine, Internal medicine, Chemistry
- MeSH
- humans, obesity, body weight, weight gain, body mass index, red meat
7 authors
From US
- Md AkheruzzamanTexas Tech University
- Marleigh HefnerTexas Tech University
- Daniel P. BallerUnited States Army Medical Command; United States Military Academy
- Shane M. ClarkBaruch College; United States Military Academy
- Zahra FeizyThe University of Texas of the Permian Basin; Texas Tech University
- Diana Maria ThomasUnited States Military Academy
Abstract
Objective
The objective of this study was to conduct a systematic review and meta-analysis of intervention trials that have determined the effect of unprocessed red meat (URM) intake on obesity-related outcomes.
Methods
The populations, interventions, controls, and outcomes (PICO) framework was used to create questions to search seven databases from July 29, 2020, to August 21, 2020. Two reviewers independently screened 5630 references. English-language intervention trials in adults testing the effect of URM on obesity-related outcomes were included. Twenty-four studies met selection criteria. A random-effects model was developed to calculate pooled effect sizes. The DerSimonian-Laird estimator was used to estimate the variance of the true effect sizes. An interactive dashboard was published to provide transparent analysis and data presentation.
Results
We found no significant effect of URM for BMI, body weight, or percent body fat based on unfiltered pooled effect sizes. Filtered pooled effect size analysis showed a slight adverse effect of URM for total cholesterol and low-density lipoprotein cholesterol.
Conclusions
Studies did not show an effect of URM on weight gain, obesity, or related metabolic conditions. This may help clinicians when considering the use of URM for patients. Longer studies may be needed for observing obesity development in case the effect of URM on weight gain is small and needs a much longer time to express.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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