Effect of the Consumption of Lean Red Meat from Beef (Pirenaica Breed) Versus Lean White Meat (Chicken) on the Gut Microbiota: A Randomized Cross-Over Study in Healthy Young Adults
Rueda-De Torre I, Plaza-Diaz J, Miguel-Berges ML, Gil A, Grasa L, Esteban LM, Sabroso-Lasa S, Campo MM, Santolaria P, Moreno LA, Santaliestra-Pasías AM
Molecular nutrition & food research · 1 citation
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Randomized controlled trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Mechanisms only
- Intake measured by
- Not stated
Who paid for it
- Funding
- Independent funding
- Government
- European Commission
- Government
- Consejo Nacional de Investigaciones Científicas y Técnicas
- Government
- European Agricultural Fund for Rural Development
- Government
- European Regional Development Fund
- Government
- Interreg
- Grants
- European Regional Development Fund (2014-2020’); European Commission (2014‐2020); European Regional Development Fund ((POCTEFA 2014‐2020)); European Commission (EFA 144/16); Interreg (2014-2020)
Based on 5 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2025-07-25 · Mol Nutr Food Res · vol. 69 · issue 21 · p. e70189
- Publisher
- Wiley
- Cited
- 2 citations · more than 67% of similar papers · 0.7× the field average
- References
- 61 works
- Access
- Open access (hybrid journal) · CC-BY-NC-ND
- Research areas
- Gut microbiota and health · Nutritional Studies and Diet · Nutrition, Health and Food Behavior
- Keywords
- White meat, Red meat, Breed, Food science, Lean meat, Gut flora, Biology, Animal science, Immunology
- MeSH
- feces, animals, chickens, cattle, humans, rna, ribosomal, 16s, diet, cross-over studies, meat, adult, female, male, young adult, gastrointestinal microbiome, red meat
11 authors
From ES
- Isabel Rueda‐De TorreUniversidad de Zaragoza; Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition; Instituto de Investigación Sanitaria Aragón
- Julio Plaza‐DíazSpanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition; Institut de Recerca Biomèdica Catalunya Sud; Universidad Internacional De La Rioja; Universitat Rovira i Virgili
- María L. Miguel‐Berges · correspondingUniversidad de Zaragoza; Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition; Centro de Investigación y Tecnología Agroalimentaria de Aragón; Instituto de Investigación Sanitaria Aragón
- Ángel Hernández GilUniversidad de Granada; Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition; Complejo Hospitalario Universitario de Granada; Parque Tecnológico de la Salud
- Laura GrasaUniversidad de Zaragoza; Centro de Investigación y Tecnología Agroalimentaria de Aragón; Instituto de Investigación Sanitaria Aragón
- Luis Mariano EstebanUniversidad de Zaragoza
Abstract
Limited evidence exists regarding the impact of meat consumption on the human gut microbiota, with factors such as animal source, production system, and cooking methods often overlooked. This study evaluates the effect of Pirenaica breed beef or conventional chicken-based diets on the gut microbiota of healthy adults. A randomized cross-over controlled trial with two 8-week periods, separated by a 5-week washout, is carried out. Participants consume either Pirenaica breed beef or chicken three times per week with their diet. Stool samples are collected at the beginning and end of each period. Gut microbiota is analyzed via amplification and sequencing of V3-V4 regions of 16S rRNA. Alpha diversity and relative abundances at phylum and genus levels are calculated. Sixteen participants are included (mean age 20.12 ± 2.36 years). Both diets induce modest changes in microbial composition, with no significant differences between groups. At the phylum level, Bacillota increased, while Synergistota, Chloroflexota, and Pseudomonadota decreased. Alpha diversity parameters declined significantly after the chicken-based diet, although overall reduction in microbial diversity was observed across both interventions. The consumption of lean red meat or lean white meat as part of habitual diet produces similar effects on the gut microbiota.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY-NC-ND).
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