Meta-analysis2025

Effect of intraoperative music intervention on anxiety and pain control in patients undergoing kidney surgery: A systematic review and meta-analysis of randomized controlled trials

Lou Y, Xu S, Gao P

Complementary therapies in medicine · 2 citations

Review labels

Funding not disclosed

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Meta-analysis (indexed by PubMed)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Funding not disclosed

Publication

Published
2025-07-30 · Complement Ther Med · vol. 95 · p. 103221
Publisher
Elsevier BV
Cited
3 citations · more than 68% of similar papers · 0.8× the field average
References
50 works
Access
Open access (journal) · CC-BY-NC-ND
Research areas
Music Therapy and Health · Patient-Provider Communication in Healthcare · Intensive Care Unit Cognitive Disorders
Keywords
Medicine, Randomized controlled trial, Anxiety, Meta-analysis, Pain control, Intervention (counseling), Postoperative pain, Surgery, Anesthesia, Internal medicine, Psychiatry
MeSH
kidney, humans, music therapy, anxiety, randomized controlled trials as topic, pain management, postoperative pain

3 authors

From CN

  • Yan LouSecond Affiliated Hospital of Jilin University
  • Shuang XuSecond Affiliated Hospital of Jilin University
  • Panpan Gao · correspondingSecond Affiliated Hospital of Jilin University

Abstract

Objectives

To report the first systematic review and meta-analysis of randomized controlled trials (RCT) for the effect of intraoperative music intervention on anxiety and pain control in patients undergoing kidney surgery.

Methods

A systematic literature search was conducted across PubMed, Embase, Web of Science, and Cochrane up to November 2024. Outcomes included visual analog score (VAS) and State-Trait Anxiety Inventory (STAI). Standardized mean differences (SMD) and 95 % confidence intervals (CI) were used for data pooling of continuous variables. In addition, sensitivity analysis was performed to assess the stability of the results. All analyses were performed using Review Manager 5.4 and STATA 15.1.

Results

The meta-analysis revealed that patients in the music intervention group had significantly lower postoperative VAS (SMD: -0.65; 95 % CI: -0.93, -0.38; P<0.00001) and STAI scores (SMD: -0.48; 95 % CI: -0.71, -0.26; P<0.0001) compared to those in the control group. Significant heterogeneity was observed for both outcomes. In addition, sensitivity analysis confirmed the stability of both outcomes, but VAS was found to have significant publication bias.

Conclusions

Music intervention can significantly reduce the postoperative VAS and STAI of patients undergoing renal surgery, and effectively control the anxiety and pain caused by surgery. Considering the potential heterogeneity, publication bias, and low regional selection bias in this study, more large-sample, multicenter RCTs are needed in the future to further confirm the effect of music intervention on pain and anxiety relief in individuals undergoing renal surgery and potential influencing factors.

Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY-NC).

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