Funded in part by Australian Eggs, Australian Eggs Ltd
Egg intake and cognitive function in healthy adults: A systematic review of the literature
Sultan N, Kellow NJ, Tuck CJ, Cheng E, MacMahon C, Biesiekierski JR
The journal of nutrition, health & aging · 0 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Systematic review (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Not stated
Who paid for it
- Funding
- Industry funded
- Industry group
- Australian Eggs
- Government
- National Health and Medical Research Council
- Industry group
- Australian Eggs Ltd
- Authors
- At least one author declares a financial tie to industry
- Grants
- National Health and Medical Research Council (2025943); Australian Eggs (GROW005)
Based on 3 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2025-10-07 · J Nutr Health Aging · vol. 29 · issue 12 · p. 100696
- Publisher
- Springer Science+Business Media
- Cited
- 3 citations · more than 69% of similar papers · 0.9× the field average
- References
- 70 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Nutritional Studies and Diet · Fatty Acid Research and Health · Antioxidant Activity and Oxidative Stress
- Keywords
- Cognition, Dementia, Intervention (counseling), Consumption (sociology), Cognitive decline, Cognitive aging
- MeSH
- humans, diet, cognition, eggs, adult, aged, middle aged, female, male, cognitive dysfunction
6 authors
From AU
- Nessmah SultanMonash University
- Nicole J. KellowMonash University
- Caroline J. TuckSwinburne University of Technology
- T.C.E. ChengMonash University
- Clare MacMahonLa Trobe University
- Jessica R. Biesiekierski · corresponding
Abstract
Background
Cognitive decline is a growing public health concern, particularly in aging populations. Eggs are a widely consumed, nutrient-dense food containing choline, phospholipids, tryptophan, and omega-3 fatty acids, which individually support cognitive processes such as memory, attention, and neurogenesis. While these individual nutrients have demonstrated benefits in supplementation studies, the cognitive effects of whole egg consumption are not well established. This systematic review aimed to evaluate the association between whole egg consumption and cognitive function in healthy adults.
Methods
A systematic search of five electronic databases (Medline, Embase, CINAHL Plus, SCOPUS, and PsychInfo) was conducted from database inception through February 2025. Studies were included if they investigated whole egg intake in relation to cognitive outcomes in healthy adults. Risk of bias was assessed using tools appropriate to study design. Due to heterogeneity in study methods, outcomes were synthesised narratively. Cognitive outcomes were categorised into domains including global cognitive function, memory, executive function, language, processing speed, and dementia risk.
Results
Eleven studies met the inclusion criteria: one pre-post intervention study, six prospective cohort studies, three cross-sectional studies, and one case-control study. Study populations were predominantly older adults and included >38,000 participants. Two studies reported a reduced risk of dementia or cognitive impairment associated with moderate egg consumption (approximately 0.5-1 egg per day), while one study found increased risk at high intake levels (Over 1 egg per day). Several studies showed improvements in memory, verbal fluency, or processing speed with moderate-but not high-egg intake. The pre-post study reported improved reaction time following eight weeks of daily egg consumption (2 eggs per day). Heterogeneity in exposure measurement and cognitive testing methods limited direct comparisons across studies.
Discussion
Moderate whole egg consumption may be associated with improvements in cognitive outcomes in healthy adults, including reduced dementia risk and better memory performance. However, findings are inconsistent and limited by differences in study design, dietary assessment, and cognitive testing. Further well-controlled intervention studies are needed to determine optimal intake levels, explore mechanisms, and assess whether eggs can be integrated meaningfully into dietary strategies to support cognitive aging. (PROSPERO registration: 408532).
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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