Study2025

Repeated low-intensity red light therapy for childhood myopia: a retrospective cohort study

Tan M, Li B, Xu Z, Wu D, Liu J, Tang W, Xu F

American journal of translational research · 1 citation

Review labels

Funding not disclosed

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Cohort study (classified by our AI screen)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Funding not disclosed

Publication

Published
2025-01-01 · Am J Transl Res · vol. 17 · issue 9 · pp. 6951–6959
Publisher
e-Century Publishing Corporation
Cited
2 citations · more than 82% of similar papers · 1.3× the field average
References
0 works
Access
Free to read
Research areas
Ophthalmology and Visual Impairment Studies · Corneal surgery and disorders · Retinopathy of Prematurity Studies
Keywords
Retrospective cohort study, Light therapy, Intervention (counseling), Red light, Cohort study

1 author

From CN

  • Meihua Tan · correspondingGanzhou People's Hospital

Abstract

Objectives

To evaluate the efficacy and safety of repeated low-intensity red light (RLRL) therapy in slowing myopia progression and improving accommodative function in children.

Methods

This retrospective cohort study reviewed electronic medical records of 202 myopic children aged 6-12 years treated at Ganzhou People's Hospital between October 2022 and October 2024. Participants were assigned to an RLRL group (n = 101; 650 nm, 1600 lx, 3 min, twice daily) or a control group (n = 101; single-vision spectacles only). Primary outcomes included axial length and spherical equivalent refraction. Secondary outcomes were uncorrected and best-corrected visual acuity, macular choroidal thickness, accommodative amplitude and facility, intraocular pressure (IOP), and corneal endothelial cell density (ECD).

Results

Baseline demographics and ocular characteristics were comparable between groups (all P > 0.05). Up to 12 months, the RLRL group exhibited significantly less axial elongation and myopic refractive progression (P 0.05).

Conclusion

RLRL therapy significantly slowed myopia progression and improved visual and accommodative function in children over 12 months, with no major safety concerns. These findings support RLRL as a promising, safe intervention for pediatric myopia control.

Abstract via Europe PMC. Copyright remains with the authors or publisher.

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