Randomized controlled trial2025Open access

Ashwagandha Does Not Enhance the Effect of High-Intensity Interval Training on Selected Energy Metabolism Parameters in Young Healthy Men

Charmas M, Jówko E, Długołęcka B, Klusiewicz A, Przybylska I, Galczak-Kondraciuk A

Nutrients · 1 citation

How it was studied

Design
Randomized controlled trial (indexed by PubMed)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Independent funding
University or hospital
Akademia Wychowania Fizycznego Józefa Piłsudskiego w Warszawie
University or hospital
Józef Piłsudski University of Physical Education in Warsaw

Based on 2 listed funder(s) and full-text disclosure statement.

Publication

Published
2025-10-16 · Nutrients · vol. 17 · issue 20 · p. 3245
Publisher
Multidisciplinary Digital Publishing Institute
Cited
3 citations · more than 92% of similar papers · 3.4× the field average
Impact
Top 10% most cited in its field
References
66 works
Access
Open access (journal) · CC-BY
Research areas
Phytochemicals and Medicinal Plants · Food Science and Nutritional Studies · Health, Education, and Aging
Keywords
Affect (linguistics), Energy metabolism, Interval training, Hormone, Energy expenditure, Adipose tissue, Athletes
MeSH
humans, aspalathus, lipids, fibronectins, double-blind method, body composition, energy metabolism, dietary supplements, adult, male, adiponectin, young adult, healthy volunteers, high-intensity interval training

6 authors

From HU, PL

  • Małgorzata Charmas · correspondingHungarian University of Sports Science; Józef Piłsudski University of Physical Education in Warsaw
  • Ewa JówkoHungarian University of Sports Science; Józef Piłsudski University of Physical Education in Warsaw
  • Barbara DługołęckaHungarian University of Sports Science; Józef Piłsudski University of Physical Education in Warsaw
  • Andrzej KlusiewiczHungarian University of Sports Science; Józef Piłsudski University of Physical Education in Warsaw
  • Iwona PrzybylskaJózef Piłsudski University of Physical Education in Warsaw
  • Anna Galczak-KondraciukJózef Piłsudski University of Physical Education in Warsaw

Abstract

Background/objectives

High-intensity interval training (HIIT) is considered an effective way in improving aerobic capacity and selected health parameters. Ashwagandha is an herb with possible health-promoting properties that may affect metabolism and performance. The aim of this study was to evaluate the effects of ashwagandha supplementation (600 mg/day) during an 8-week HIIT on body composition, lipid profile and hormone levels related to energy homeostasis in healthy young men.

Methods

The study was randomised, double-blind and placebo-controlled (Placebo group, PL, n = 20; ashwagandha, A, n = 18). HIIT was conducted on a rowing ergometer (3 times per week, 5-7 series of 1.5 min at 85-95% of maximum power, with intervals of 1.5 min at 70 W). Body composition (BIA, Tanita TBF 300P), serum lipid profile (tChol, HDL-cholesterol, LDL-cholesterol, TG) and serum levels of adiponectin, asprosin and irisin were analysed before (term 1) and after the8-week study (term 2). Both the lipid and hormonal profiles were measured in three time points: pre- and post-graded exercise test and after 24 h recovery period.

Results

Analysis showed no effect of training or supplementation on body composition and lipid profile (p > 0.05). In turn, the 8-week HIIT decreased resting levels of adiponectin and increased irisin levels post-exercise and after 24 h (p < 0.05).

Conclusions

In young, healthy men, an 8-week HIIT programme significantly affects selected hormones related to energy metabolism of adipose (adiponectin) and muscle (irisin) tissues, but ashwagandha supplementation did not significantly affect any of the hormonal parameters analysed.

Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).

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