Effect of increased venous blood flow with acute passive heating on volume and compliance in the calf vein in young adults
Iimura Y, Oue A
Physiological reports · 1 citation
How it was studied
- Design
- Controlled clinical trial (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
- Government
- Ministry of Education, Culture, Sports, Science and Technology
- Government
- Japan Society for the Promotion of Science
- Government
- MEXT | Japan Society for the Promotion of Science (JSPS)
- Grants
- Ministry of Education, Culture, Sports, Science and Technology (18K10974); Japan Society for the Promotion of Science (18K10974)
Based on 3 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2025-12-01 · Physiol Rep · vol. 13 · issue 23 · p. e70700
- Publisher
- Wiley
- Cited
- 0 citations · more than 36% of similar papers · 0.0× the field average
- References
- 55 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Thermoregulation and physiological responses · Diagnosis and Treatment of Venous Diseases · Cardiovascular Health and Disease Prevention
- Keywords
- Cuff, Compliance (psychology), Thigh, Blood volume, Calf muscle, Venous return curve, Vein
- MeSH
- leg, veins, humans, blood volume, regional blood flow, compliance, adult, female, male, hot temperature, young adult
2 authors
From JP
- YASUO IIMURAToyo University
- Anna Oue · correspondingToyo University
Abstract
Arterial endothelial function-impairment of which is a risk factor for cardiovascular disease-increases after acute passive heating; however, whether venous properties (volume and compliance) also increase remains unclear. Moreover, it is unknown whether venous congestion induced by proximal thigh cuff inflation and passive heating exerts opposing effects on the venous properties. Therefore, in 21 young healthy adults, we determined the acute effects of passive heating (42°C) of the left leg and concurrent cuff inflation (80-110 mmHg) of the right leg for 40 min on venous properties. Specifically, before (Pre) and 60 min after (Post 60) the single manipulation, the venous volume and compliance in both legs were determined from the change in calf volume during a cuff deflation protocol. After passive heating, the calf venous compliance decreased (Pre, 0.090 ± 0.032 mL/dL/mmHg; Post 60, 0.084 ± 0.031 mL/dL/mmHg; p 0.05). While the volume (Pre, 3.32 ± 1.08 mL/dL; Post 60, 3.19 ± 0.86 mL/dL; p > 0.05) and compliance (Pre, 0.091 ± 0.028 mL/dL/mmHg; Post 60, 0.092 ± 0.033 mL/dL/mmHg; p > 0.05) in calf veins did not alter after thigh cuff inflation. These results suggest that acute passive heating decreases calf venous compliance with no change in calf venous volume, while thigh cuff inflation does not alter volume and compliance in the calf veins in healthy young adults.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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