Case report2026

Reversible Cerebral Vasoconstriction Syndrome Triggered by Whole-Body Cryotherapy in a Teenager

Dantas M, Zilinskas K, Shen C, Summer A

Journal of child neurology · 0 citations

Review labels

Funding not disclosed

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Case report (indexed by PubMed)
Studied in
People
Main outcome
Clinical events such as disease or death

Who paid for it

Funding
Funding not disclosed

Publication

Published
2025-12-26 · J Child Neurol · vol. 41 · issue 8 · pp. 1193–1196
Publisher
SAGE Publishing
Cited
0 citations · more than 53% of similar papers · 0.0× the field average
References
12 works
Access
Paywalled
Research areas
Neurological Complications and Syndromes · Anesthesia and Neurotoxicity Research · Electrolyte and hormonal disorders
Keywords
Cryotherapy, Vasoconstriction, Reversible cerebral vasoconstriction syndrome, Stroke (engine), Intervention (counseling), Vasoactive
MeSH
humans, vasospasm, intracranial, cryotherapy, vasoconstriction, adolescent, male

4 authors

From US

  • Marina Dantas · correspondingChildren's Mercy Hospital
  • Kasparas ZilinskasMedical University of South Carolina
  • Christina ShenMedical University of South Carolina
  • Andrea P. SummerMedical University of South Carolina

Abstract

Reversible cerebral vasoconstriction syndrome (RCVS) is uncommon in childhood. Although it usually has favorable outcomes, it still carries a risk of serious complications, including intracranial bleeding and ischemic stroke. RCVS may arise idiopathically, from vasoactive triggers or from daily activities such as defecation, urination, exertion, or sexual activity. Whole-body cryotherapy (WBC) is not officially recognized as a trigger for RCVS. We present a case of RCVS in an adolescent who underwent a WBC session preceding his symptoms and diagnosis. Although an association between cold weather exposure and stroke is recognized, the connection between cold weather and RCVS is less established. Furthermore, there is limited to no evidence linking WBC to stroke or RCVS. We aim to highlight a potential side effect of WBC, an increasingly popular intervention lacking evidence-based benefits and well-studied side effects.

Abstract via Europe PMC. Copyright remains with the authors or publisher.

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