Analgesic Efficacy of Low-Level Laser Therapy for Postoperative Endodontic Pain: A Systematic Review and Meta-Analysis
Bonacina G, Hartmann RC, Gomes MS, Böttcher DE
Australian endodontic journal : the journal of the Australian Society of Endodontology Inc · 0 citations
How it was studied
- Design
- Meta-analysis (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
- Government
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Government
- Coordination for Funding and Support of Tertiary Education (CAPES), Brazil, Finance Code
Based on 2 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2026-01-06 · Aust Endod J · vol. 52 · issue 1 · pp. 310–322
- Publisher
- Wiley
- Cited
- 1 citation · more than 80% of similar papers · 2.6× the field average
- References
- 31 works
- Access
- Open access (hybrid journal) · CC-BY
- Research areas
- Laser Applications in Dentistry and Medicine · Endodontics and Root Canal Treatments · Dental Anxiety and Anesthesia Techniques
- Keywords
- Analgesic, Placebo, Low level laser therapy, Postoperative pain, Endodontic therapy, Pain control, Clinical trial, Randomized controlled trial
- MeSH
- humans, pain measurement, treatment outcome, root canal therapy, low-level light therapy, postoperative pain
4 authors
From BR
- Gabriela BonacinaUniversidade Feevale; Pontifícia Universidade Católica do Rio Grande do Sul
- Rafael Chies HartmannPontifícia Universidade Católica do Rio Grande do Sul
- Maximiliano Schünke GomesPontifícia Universidade Católica do Rio Grande do Sul
- Daiana Elisabeth Böttcher · correspondingPontifícia Universidade Católica do Rio Grande do Sul
Abstract
This systematic review analysed the analgesic efficacy of low-level laser therapy (LLLT) compared to conventional drug therapy and placebo for postoperative pain in endodontics. PubMed, PubMed Central, Scopus, LILACS, SciELO, Virtual Health Library, Embase and Open Gray were searched. Clinical trials assessing pain intensity were included. Risk of bias was assessed using the RoB 2.0 tool. Nine studies were included, five classified as having low risk of bias. Eight studies demonstrated that LLLT was more effective in modulating postoperative pain compared to control interventions. Meta-analysis of five studies (I2 = 31%) showed statistically significant pain reduction with LLLT in comparison with placebo after 1 day (VAS mean difference = -0.56; 95% CI = [-0.74 to -0.38]; p < 0.001). LLLT may improve postoperative pain control after endodontic treatment. Additional high-quality studies are necessary to strengthen the evidence base for LLLT's analgesic efficacy in endodontic applications.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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