Meta-analysis2026

Effect of music intervention on anxiety in surgical patients: Systematic review and meta-analysis of randomized controlled trials

Yu Y, Sabran K, Wang G, Chen Z

General hospital psychiatry · 1 citation

Review labels

Funding not disclosed

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Meta-analysis (indexed by PubMed)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Funding not disclosed

Publication

Published
2026-01-13 · Gen Hosp Psychiatry · vol. 99 · pp. 50–65
Publisher
Elsevier BV
Cited
1 citation · more than 83% of similar papers · 2.6× the field average
References
60 works
Access
Paywalled
Research areas
Music Therapy and Health · Intensive Care Unit Cognitive Disorders · Family and Patient Care in Intensive Care Units
Keywords
Randomized controlled trial, Anxiety, Perioperative, Intervention (counseling), Music therapy
MeSH
humans, music therapy, perioperative care, surgical procedures, operative, anxiety, randomized controlled trials as topic

4 authors

From MY

  • Yang YuUniversiti Sains Malaysia
  • Kamal Sabran · correspondingUniversiti Sains Malaysia
  • Guoqing WangUniversiti Sains Malaysia
  • Ziyue ChenUniversiti Sains Malaysia

Abstract

Background

During the patient's surgery, they tend to experience anxiety a lot which sometimes affect their outcomes in a negative way. Music intervention which is a non-pharmacological intervention is being used increasingly to address perioperative anxiety among patients. However, the existing evidence shows varied quality of studies, intervention timing and patient characteristics. This study aimed to analysis RCT evidence on the effectiveness of music intervention in reducing anxiety among adult surgical patients.

Methods

We searched 5 databases following PRISMA guidelines. The search scope covers the period from database creation to July 2025. Eligible studies included RCTs examining the impact of music as an approach for surgical patients. Risk of bias was assessed using the Cochrane tool. We combined standardized mean differences with a random effects model. The intervention timing, type of anesthesia, gender distribution and average age were studied in subgroup analyses. Sensitivity analyses and publication bias evaluations were done.

Results

A total of 33 RCTs (n = 3793) were included and the data from 8 statistical outliers was removed, leaving 25 studies for the primary meta-analysis. Music intervention significantly reduced perioperative anxiety (SMD = -0.50, 95% CI -0.60 to -0.39, p 2 = 33.3%). There were greater outcomes in those receiving multi-phase interventions, local/regional anesthesia, males, and older patients. Although there were no significant subgroup differences. Sensitivity analysis confirmed robustness of findings and no meaningful publication bias was detected.

Conclusion

Music intervention, as a safe, effective, and easy-to-implement intervention strategy, can help reduce perioperative anxiety in patients undergoing various surgeries in different clinical settings. Including music protocols in standard perioperative care may help enhance patient experience and mental well-being.

Abstract via Europe PMC. Copyright remains with the authors or publisher.

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